Organoselenium compounds as mimics of selenoproteins and thiol modifier agents

NV Barbosa, CW Nogueira, PA Nogara… - Metallomics, 2017 - academic.oup.com
Selenium is an essential trace element for animals and its role in the chemistry of life relies
on a unique functional group: the selenol (–SeH) group. The selenol group participates in …

Adaptive responses of sterically confined intramolecular chalcogen bonds

K Selvakumar, HB Singh - Chemical Science, 2018 - pubs.rsc.org
The responsive behavior of an entity towards its immediate surrounding is referred to as an
adaptive response. The adaptive responses of a noncovalent interaction at the molecular …

Synthesis, Structure, and Glutathione Peroxidase‐Like Activity of Amino Acid Containing Ebselen Analogues and Diaryl Diselenides

K Selvakumar, P Shah, HB Singh… - Chemistry–A European …, 2011 - Wiley Online Library
The synthesis of some ebselen analogues and diaryl diselenides, which have amino acid
functions as an intramolecularly coordinating group (Se⋅⋅⋅ O) has been achieved by the …

Anti‐cancer potential of selenium‐and tellurium‐containing species: opportunities abound!

HL Seng, ERT Tiekink - Applied Organometallic Chemistry, 2012 - Wiley Online Library
An overview highlighting the anti‐cancer potential of (bio‐essential) selenium‐and tellurium‐
containing species, with an emphasis on biological targets and mechanisms of action, is …

Cyclic seleninate esters, spirodioxyselenuranes and related compounds: new classes of biological antioxidants that emulate glutathione peroxidase

KN Sands, TA Tuck, TG Back - Chemistry–A European Journal, 2018 - Wiley Online Library
Selenium compounds play an important role in redox homeostasis in living organisms. One
of their major functions is to suppress the harmful effects of hydrogen peroxide …

An Overview of organoselenium chemistry: From fundamentals to synthesis

VK Jain - 2017 - books.rsc.org
Selenium is a member of the group 16 elements (O, S, Se, Te and radioactive Po),
collectively known as chalcogens. It was discovered in 1817 by JJ Berzelius in the reddish …

Synthesis and antioxidant activities of N-thiophenyl ebselenamines: a 77 Se {1 H} NMR mechanistic study

M Kumar, VP Singh - New Journal of Chemistry, 2022 - pubs.rsc.org
The step-by-step redox process of bis-[2-phenyl-1, 2-benzisoselenazol-3 (2H)-one-7-yl]
diazene ie azo-bis-ebselen in the presence of PhSH and H2O2 was reported using 77Se …

Synthesis of Cyclic Selenenate/Seleninate Esters Stabilized by ortho‐Nitro Coordination: Their Glutathione Peroxidase‐Like Activities

VP Singh, HB Singh, RJ Butcher - Chemistry–An Asian Journal, 2011 - Wiley Online Library
The syntheses of selenenate/seleninate esters and related derivatives by aromatic
nucleophilic substitution (SNAr) reactions of 2‐bromo‐3‐nitrobenzylalcohol (13) and 2 …

Organomercury (ii) and tellurium (ii) compounds with the “pincer” ligand 2, 6-[O (CH 2 CH 2) 2 NCH 2] 2 C 6 H 3–stabilization of an unusual organotellurium (ii) …

A Beleaga, VR Bojan, A Pöllnitz, CI Raţ… - Dalton Transactions, 2011 - pubs.rsc.org
The reaction of RH (1) with Hg (OAc) 2, in EtOH, gave the acetate RHgOAc (2)[R= 2, 6-[O
(CH2CH2) 2NCH2] 2C6H3]. The corresponding RHgCl (3) was obtained from 2 and LiCl …

Synthesis strategies for organoselenium compounds and their potential applications in human life

PP Phadnis - Handbook on Synthesis Strategies for Advanced …, 2021 - Springer
This article describes the prime role of selenium (Se) and its compounds in mammalian
biochemical systems, performing diverse functions like maintenance of health through …