Fertility preservation in women

J Donnez, MM Dolmans - Nature Reviews Endocrinology, 2013 - nature.com
In women,∼ 10% of cancers occur in those< 45 years old. Chemotherapy, radiotherapy and
bone marrow transplantation can cure> 90% of girls and young women with diseases that …

Fertility preservation during cancer treatment: clinical guidelines

KA Rodriguez-Wallberg, K Oktay - Cancer management and …, 2014 - Taylor & Francis
The majority of children, adolescents, and young adults diagnosed with cancer today will
become long-term survivors. The threat to fertility that cancer treatments pose to young …

Long-term safety of letrozole and gonadotropin stimulation for fertility preservation in women with breast cancer

J Kim, V Turan, K Oktay - The Journal of Clinical Endocrinology …, 2016 - academic.oup.com
Abstract Context and Objective: There has been increased attention to the issue of fertility
preservation (FP). We aimed to investigate the long-term safety of FP via controlled ovarian …

Ovarian follicle depletion induced by chemotherapy and the investigational stages of potential fertility-protective treatments—a review

X Hao, A Anastácio, K Liu… - International journal of …, 2019 - mdpi.com
Ovarian follicle pool depletion, infertility, and premature menopause are all known sequelae
of cancer treatment that negatively impact the quality of life of young cancer survivors. The …

[HTML][HTML] Current approach to fertility preservation by embryo cryopreservation

G Bedoschi, K Oktay - Fertility and sterility, 2013 - Elsevier
The ovaries are susceptible to damage following treatment with gonadotoxic chemotherapy,
pelvic radiotherapy, and/or ovarian surgery. Gonadotoxic treatments have also been used in …

The late effects of cancer treatment on female fertility and the current status of fertility preservation—a narrative review

KA Rodriguez-Wallberg, Y Jiang, T Lekberg… - Life, 2023 - mdpi.com
Fertility counseling should be offered to all individuals of young reproductive age early in the
patient's trajectory following a cancer diagnosis. Systemic cancer treatment and …

Reproductive decision-making in women with BRCA1/2 mutations

JL Chan, LNC Johnson, MD Sammel… - Journal of genetic …, 2017 - Springer
Expanded genetic testing of BRCA mutations has led to identification of more reproductive-
aged women who test positive for the mutation which might impact attitudes and decisions …

Fertility and pregnancy issues in BRCA-mutated breast cancer patients

M Lambertini, O Goldrat, A Toss, HA Azim Jr… - Cancer treatment …, 2017 - Elsevier
Fertility and pregnancy-related issues represent one of the main areas of concerns for young
women with breast cancer. Carrying a germline deleterious BRCA mutation adds additional …

[HTML][HTML] Increased chemotherapy-induced ovarian reserve loss in women with germline BRCA mutations due to oocyte deoxyribonucleic acid double strand break …

KH Oktay, G Bedoschi, SB Goldfarb, E Taylan, S Titus… - Fertility and sterility, 2020 - Elsevier
Objective To assess whether woman who have BRCA mutations (WBM) experience more
declines in ovarian reserve after chemotherapy treatment, as it induces oocyte death by …

Safety of fertility preservation in breast cancer patients in a register-based matched cohort study

KA Rodriguez-Wallberg, S Eloranta, K Krawiec… - Breast cancer research …, 2018 - Springer
Purpose To determine if women with breast cancer that undergo fertility preservation (FP),
with or without hormonal stimulation, present with an increased risk of breast cancer …