Globally, esophageal cancer (EC) is the 6th leading cause of cancer-related deaths and the
second deadliest gastrointestinal cancer. Multiple genetic and epigenetic factors, such as …

Urological cancers are considered as life-threatening diseases around the world. Bladder
cancer is one of the most malignant urological tumors with high mortality and morbidity …

The etiology of Parkinson's disease (PD) is poorly understood, and is strongly suspected to
include both genetic and environmental factors. In this context, it is essential to investigate …

The NLR family pyrin domain containing 3 (NLRP3) promotes the growth of colorectal
cancer (CRC). However, the therapeutic effect of NLRP3 inhibition on CRC cell progression …

Inflammatory bowel disease is a heterogeneous intestinal inflammatory disorder, including
ulcerative colitis (UC) and Crohn's disease (CD). Existing studies have shown that the …

Adolescents and young adults (AYA) with rhabdomyosarcoma (RMS) form a subgroup of
patients whose optimal clinical management and best possible access to care remain a …

FBXW7, a member of the F-box protein family within the ubiquitin–proteasome system,
performs an indispensable role in orchestrating cellular processes through ubiquitination …

Inflammasomes contribute to colorectal cancer signaling by primarily inducing inflammation
in the surrounding tumor microenvironment. Its role in inflammation is receiving increasing …

Phosphoenolpyruvate carboxykinase (PEPCK) is a key enzyme in the glyconeogenesis
pathway. The AMP‐activated protein kinase alpha (AMPK‐α) pathway regulates PEPCK …

Hepatocellular carcinoma (HCC) is the third most common cause of cancer-related death.
Therefore, it is critical for researchers to understand molecular biology in greater depth. In …