[HTML][HTML] Mouse models for studying angiogenesis and lymphangiogenesis in cancer

L Eklund, M Bry, K Alitalo - Molecular oncology, 2013 - Elsevier
The formation of new blood vessels (angiogenesis) is required for the growth of most tumors.
The tumor microenvironment also induces lymphangiogenic factors that promote metastatic …

Multilayer mounting enables long-term imaging of zebrafish development in a light sheet microscope

A Kaufmann, M Mickoleit, M Weber… - Development, 2012 - journals.biologists.com
Light sheet microscopy techniques, such as selective plane illumination microscopy (SPIM),
are ideally suited for time-lapse imaging of developmental processes lasting several hours …

How Non-invasive in vivo Cell Tracking Supports the Development and Translation of Cancer Immunotherapies

M Iafrate, GO Fruhwirth - Frontiers in Physiology, 2020 - frontiersin.org
Immunotherapy is a relatively new treatment regimen for cancer, and it is based on the
modulation of the immune system to battle cancer. Immunotherapies can be classified as …

Optical tomography complements light sheet microscopy for in toto imaging of zebrafish development

A Bassi, B Schmid, J Huisken - Development, 2015 - journals.biologists.com
Fluorescently labeled structures can be spectrally isolated and imaged at high resolution in
living embryos by light sheet microscopy. Multimodal imaging techniques are now needed to …

PS F: Polarized Spiral Point Spread Function for Single-Shot 3D Sensing

B Ghanekar, V Saragadam, D Mehra… - … on Pattern Analysis …, 2022 - ieeexplore.ieee.org
We propose a compact snapshot monocular depth estimation technique that relies on an
engineered point spread function (PSF). Traditional approaches used in microscopic super …

Accelerated Optical Projection Tomography Applied to In Vivo Imaging of Zebrafish

T Correia, N Lockwood, S Kumar, J Yin, MC Ramel… - PLOS …, 2015 - journals.plos.org
Optical projection tomography (OPT) provides a non-invasive 3-D imaging modality that can
be applied to longitudinal studies of live disease models, including in zebrafish. Current …

[HTML][HTML] Cousins at work: how combining medical with optical imaging enhances in vivo cell tracking

A Volpe, E Kurtys, GO Fruhwirth - … journal of biochemistry & cell biology, 2018 - Elsevier
Microscopy and medical imaging are related in their exploitation of electromagnetic waves,
but were developed to satisfy differing needs, namely to observe small objects or to look …

OptiJ: Open-source optical projection tomography of large organ samples

PP Vallejo Ramirez, J Zammit, O Vanderpoorten… - Scientific reports, 2019 - nature.com
The three-dimensional imaging of mesoscopic samples with Optical Projection Tomography
(OPT) has become a powerful tool for biomedical phenotyping studies. OPT uses visible …

Optical projection tomography as a quantitative tool for analysis of cell morphology and density in 3D hydrogels

B Belay, JT Koivisto, J Parraga, O Koskela… - Scientific Reports, 2021 - nature.com
Assessing cell morphology and function, as well as biomaterial performance in cell cultures,
is one of the key challenges in cell biology and tissue engineering (TE) research. In TE …

Visualising apoptosis in live zebrafish using fluorescence lifetime imaging with optical projection tomography to map FRET biosensor activity in space and time

N Andrews, MC Ramel, S Kumar… - Journal of …, 2016 - Wiley Online Library
Fluorescence lifetime imaging (FLIM) combined with optical projection tomography (OPT)
has the potential to map Förster resonant energy transfer (FRET) readouts in space and time …