Modeling to understand plant protein structure-function relationships—implications for seed storage proteins

F Rasheed, J Markgren, M Hedenqvist, E Johansson - Molecules, 2020 - mdpi.com
Proteins are among the most important molecules on Earth. Their structure and aggregation
behavior are key to their functionality in living organisms and in protein-rich products …

[HTML][HTML] Computer-aided drug discovery in plant pathology

G Shanmugam, J Jeon - The plant pathology journal, 2017 - ncbi.nlm.nih.gov
Control of plant diseases is largely dependent on use of agrochemicals. However, there are
widening gaps between our knowledge on plant diseases gained from genetic/mechanistic …

E7 oncoprotein of human papillomavirus: Structural dynamics and inhibitor screening study

M Aarthy, D Kumar, R Giri, SK Singh - Gene, 2018 - Elsevier
Human papillomavirus (HPV) has been the primary causative agent of cervical cancer, the
most threatening cancer affecting millions of women worldwide. HPV, a small non …

In silico identification of natural product inhibitors against Octamer-binding transcription factor 4 (Oct4) to impede the mechanism of glioma stem cells

C Nayak, SK Singh - Plos one, 2021 - journals.plos.org
Octamer-binding transcription factor 4 (Oct4) is a core regulator in the retention of stemness,
invasive, and self-renewal properties in glioma initiating cells (GSCs) and its overexpression …

Molecular recognition of avirulence protein (avrxa5) by eukaryotic transcription factor xa5 of rice (Oryza sativa L.): Insights from molecular dynamics simulations

B Dehury, J Maharana, BR Sahoo, J Sahu… - Journal of Molecular …, 2015 - Elsevier
The avirulence gene avrxa5 of bacterial blight pathogen Xanthomonas oryzae pv. oryzae
(Xoo) recognized by the resistant rice lines having corresponding resistance (xa5) gene in a …

A computational investigation on Rho-related GTP-binding protein RhoB through molecular modeling and molecular dynamics simulation study

SK Paul, CL Nahar Metu, SK Sutihar, M Saddam… - bioRxiv, 2023 - biorxiv.org
Backgorund RhoB is a key member of the Rho family of isoprenylated small GTPases which
modulate the cellular cytoskeletal organization. It has a crucial role in the neoplastic …

Ribonucleotide reductase as a drug target against drug resistance Mycobacterium leprae: A molecular docking study

PS Mohanty, AK Bansal, F Naaz, UD Gupta… - Infection, Genetics and …, 2018 - Elsevier
Leprosy is a chronic infection of skin and nerve caused by Mycobacterium leprae. The
treatment is based on standard multi drug therapy consisting of dapsone, rifampicin and …

Opportunities for Bioinformatics Tools for the Management of Rice Bacterial Diseases

P Saini, S Yashveer, NS Redhu… - Bacterial Diseases of …, 2023 - taylorfrancis.com
One of the most critical constraints is bacterial diseases in rice production. The diagnosis,
identification, and management of plant pathogens are requisite for disease control. The …

In-silico Characterization and Comparative Analysis of BLB Disease Resistance Xa genes in Oryza sativa

MA Ramzan, H Asghar, A Rehman, M Rashid… - 2020 - preprints.org
Globally, rice is utilized as staple food, belongs to the family Poaceae. From the past few
decades under variable climate conditions, it greatly affected by the bacterial leaf blight …

[PDF][PDF] Molecular recognition of avirulence protein (avrxa5) by

BDJM Bikash - Nucleic Acids Res, 2012 - academia.edu
The avirulence gene avrxa5 of bacterial blight pathogen Xanthomonas oryzae pv. oryzae
(Xoo) recognized by the resistant rice lines having corresponding resistance (xa5) gene in a …