Is low‐level alcohol consumption really health‐protective? A critical review of approaches to promote causal inference and recent applications

R Visontay, L Mewton, M Sunderland… - Alcohol: Clinical and …, 2024 - Wiley Online Library
Heavy and disordered alcohol consumption is a known risk factor for several health
conditions and is associated with considerable disease burden. However, at low‐to …

Association between excessive alcohol consumption and incident diabetes mellitus among Japanese based on propensity score matching

C Cao, C Wei, Y Han, J Luo, P Xi, J Chen, X Xiao… - Scientific Reports, 2024 - nature.com
The available evidence on the connection between excessive alcohol consumption and
diabetes is controversial. Therefore, the primary objective of this investigation was to …

MR Corge: sensitivity analysis of Mendelian randomization based on the core gene hypothesis for polygenic exposures

W Zhang, CY Su, S Yoshiji, T Lu - Bioinformatics, 2024 - academic.oup.com
Mendelian randomization is being utilized to assess causal effects of polygenic exposures,
where many genetic instruments are subject to horizontal pleiotropy. Existing methods for …

The influence of trinucleotide repeats in the androgen receptor gene on androgen-related traits and diseases

T Sasako, Y Ilboudo, KYH Liang, Y Chen… - The Journal of …, 2024 - academic.oup.com
Context Trinucleotide repeats in the androgen receptor have been proposed to influence
testosterone signaling in men, but the clinical relevance of these trinucleotide repeats …

Threshold effect of atherogenic index of plasma on type 2 diabetes mellitus and modification by uric acid in normal-weight adults with hypertension

Y Tao, T Wang, W Zhou, L Zhu, C Yu, H Bao… - Frontiers in …, 2024 - frontiersin.org
Background The association between atherogenic index of plasma (AIP) and type 2
diabetes mellitus (T2DM) in normal-weight individuals with hypertension remains unclear …

Analysis of data from the NHANES 1999–2018 and Mendelian randomization studies reveals the relationship between alcohol use and rheumatoid arthritis

X Yang, X Long, P Xiao, Q Ge, L Zhang, X Wang - Nutrition Journal, 2024 - Springer
Rheumatoid arthritis (RA) is a complex multifactorial autoimmune disease affected by
genetics and environmental factors. The relationship between alcohol consumption and RA …

A Mendelian randomization study of alcohol use and cardiometabolic disease risk in a multi‐ancestry population from the Million Veteran Program

RL Kember, CT Rentsch, J Lynch… - Alcohol: Clinical and …, 2024 - Wiley Online Library
Background Observational studies link moderate alcohol consumption to reduced risk of
cardiometabolic diseases, including coronary heart disease (CHD) and type 2 diabetes …

Improved characterization of gene-environment interactions for vitamin D through variance quantitative trait loci

T Lu, W Zhang, C Robinson-Cohen, CD Engelman… - medRxiv, 2024 - medrxiv.org
Background Understanding gene-environment interaction effects influencing vitamin D
status may refine nutrition and public health strategies for vitamin D deficiency. Recent …

[HTML][HTML] Chronic Low Back Pain Causal Risk Factors Identified by Mendelian Randomization: a Cross-Sectional Cohort Analysis

P Zheng, A Scheffler, S Ewing, T Hue, S Jones… - medRxiv, 2024 - pmc.ncbi.nlm.nih.gov
Abstract Background Context There are a number of risk factors-from biological,
psychological, and social domains-for non-specific chronic low back pain (cLBP). Many …

Escala Diabetes-Prev: validación en medidas preventivas de diabetes tipo 2 en habitantes cajamarquinos, diseño de validación

O Linares-Vásquez, YY Díaz-Dávila… - Revista …, 2024 - revistas.udes.edu.co
Introducción: Las medidas preventivas son eficaces para reducir la prevalencia de diabetes,
por ello contar con instrumentos válidos para su evaluación es prioritario. Objetivo: Validar …