Pharmacokinetic considerations for use of artemisinin-based combination therapies against falciparum malaria in different ethnic populations
Introduction: Artemisinin-based combination therapy (ACT) is used extensively as first-line
treatment for uncomplicated falciparum malaria. There has been no rigorous assessment of …
treatment for uncomplicated falciparum malaria. There has been no rigorous assessment of …
Population pharmacokinetic properties of sulfadoxine and pyrimethamine: a pooled analysis to inform optimal dosing in African children with uncomplicated malaria
M de Kock, J Tarning, L Workman… - Antimicrobial agents …, 2018 - Am Soc Microbiol
Sulfadoxine-pyrimethamine with amodiaquine is recommended by the World Health
Organization as seasonal malaria chemoprevention for children aged 3 to 59 months in the …
Organization as seasonal malaria chemoprevention for children aged 3 to 59 months in the …
Ebola vaccine trials: a race against the clock
G Chowell, C Viboud - The Lancet. Infectious diseases, 2015 - pubmed.ncbi.nlm.nih.gov
Ebola vaccine trials: a race against the clock Ebola vaccine trials: a race against the clock
Lancet Infect Dis. 2015 Jun;15(6):624-6. doi: 10.1016/S1473-3099(15)70159-3. Epub 2015 Apr …
Lancet Infect Dis. 2015 Jun;15(6):624-6. doi: 10.1016/S1473-3099(15)70159-3. Epub 2015 Apr …
Sulfonamides
NE Holmes, ML Grayson - Kucers' The Use of Antibiotics, 2017 - taylorfrancis.com
The first sulfonamide (sulphonamide) compound of clinical importance, prontosil rubrum,
was synthesized in Germany in 1932 and first used as a chemotherapeutic agent in 1935 …
was synthesized in Germany in 1932 and first used as a chemotherapeutic agent in 1935 …
A localised threat to an excellent antimalarial drug
GO Gbotosho, O Akinola - The Lancet Infectious Diseases, 2015 - thelancet.com
5 Worldwide Antimalarial Resistance Network (WWARN) AL Dose Impact Study Group. The
effect of dose on the antimalarial efficacy of artemether–lumefantrine: a systematic review …
effect of dose on the antimalarial efficacy of artemether–lumefantrine: a systematic review …
Therapeutic Efficacy of Artesunate–Amodiaquine Combinations and the Plasma and Saliva Concentrations of Desethylamodiaquine in Children With Acute …
A Sowunmi, GO Gbotosho, CT Happi… - American Journal of …, 2013 - journals.lww.com
The treatment efficacy of artesunate–amodiaquine (AQ) coformulated or copackaged, and
the plasma and saliva concentrations of desethylamodiaquine (DEAQ), the active metabolite …
the plasma and saliva concentrations of desethylamodiaquine (DEAQ), the active metabolite …
[PDF][PDF] Research Article Can Co-administration of Sulfadoxine-pyremathamine and Single-dose Activated Charcoal Reduce the Chances of Adverse Reactions in …
EP Madu - 2016 - researchgate.net
Background: Adverse drug reactions from the use of sulfadoxine-pyremathamine (fansidar)
as chemoprophylaxis and in uncomplicated malaria have been well reported. However, this …
as chemoprophylaxis and in uncomplicated malaria have been well reported. However, this …
[PDF][PDF] Monitor evaluate improve: TDR results 2013 report: measuring for improvement
UNICEF, World Health Organization - 2014 - apps.who.int
1. Summary The 2013 Results Report is built upon a new set of performance targets and
indicators in line with the 2012-2017 strategic plan and the current Performance Assessment …
indicators in line with the 2012-2017 strategic plan and the current Performance Assessment …
DETERMINANTS OF RESPONSES TO ANTIMALARIAL DRUGS IN CHILDREN WITH UNCOMPLICATED PLASMODIUM FALCIPARUM MALARIA
AO SIJUADE - 2011 - repository.ui.edu.ng
Drug resistance is a challenge to malaria control efforts and several factors including
parasite genetics, host factors and pharmacokinetics may contribute to the selection of drug …
parasite genetics, host factors and pharmacokinetics may contribute to the selection of drug …