Despite lack of paediatric labelling, contributions to the literature on paediatric applications
of dexmedetomidine have increased over recent years. Dexmedetomidine possesses many …

More than 200 studies and reports have been published regarding the use of
dexmedetomidine in infants and children. We reviewed the English literature to summarize …

Objective To investigate the safety, efficacy, and pharmacokinetic profile of
dexmedetomidine in preterm and full-term neonates≥ 28 to≤ 44 weeks gestational age …

BACKGROUND Chronic obstructive pulmonary disease (COPD) is a risk factor that
increases the incidence of postoperative cardiopulmonary morbidity and mortality after lung …

Importance of the field: Dexmedetomidine is an α2-adrenoceptor agonist with sedative,
anxiolytic and analgesic properties. It is used off-label in pediatric patients due to its efficacy …

This study aimed to provide a general description of the cardiovascular and hemodynamic
effects of dexmedetomidine and an evidence-based review of the literature regarding its use …

BACKGROUND: Dexmedetomidine, an α-2 receptor agonist, is widely used in children with
cardiac disease. Significant hemodynamic responses, including systemic and pulmonary …

BACKGROUND: Dexmedetomidine is a highly selective α 2-adrenoceptor agonist with
sedative, anxiolytic, and analgesic properties that has minimal effects on respiratory drive. Its …

Objective: To evaluate the dose-response relationship of dexmedetomidine in infants with
congenital heart disease postoperative from open heart surgery. Design: Prospective open …

Objectives: Dexmedetomidine (DEX) is a highly selective alpha-2 adrenergic receptor
agonist, which is the main sedative in the intensive care unit. This study aims to investigate …