Hemolysis is a pathological feature of several diseases of diverse etiology such as
hereditary anemias, malaria, and sepsis. A major complication of hemolysis involves the …

Haptoglobin (Hp) belongs to the family of acute-phase plasma proteins and represents the
most important plasma detoxifier of hemoglobin (Hb). The basic Hp molecule is a tetrameric …

Background Red blood cell distribution width (RDW) to albumin ratio (RAR) is associated
with poor prognosis in diabetic comorbidities and cancer. However, the association between …

Sepsis is associated with exacerbated inflammatory response which subsequently results in
multiple organ dysfunction. Sepsis accounts for high mortality and morbidity among …

Invasive bacterial disease is well described in immunocompromised hosts, including those
with malaria infection. One bacterial infection frequently observed in children with …

Large variability in COVID-19 clinical progression urges the need to find the most relevant
biomarkers to predict patients' outcomes. We evaluated iron metabolism and immune …

Background Sepsis is a life-threatening and inflammatory disease with high morbidity and
mortality. Red blood cell distribution width to platelet count ratio (RPR) was known as an …

Post mortem tryptase is a commonly-used ancillary test in the investigation of possible
anaphylactic deaths. Ante mortem tryptase interpretation differs from post mortem …

Globally, malaria continues to be an enormous public health burden, with concomitant
parasite-induced damage to the gastrointestinal (GI) barrier resulting in bacteremia …

Background Heme oxygenase one (HO-1) is considered a poor prognostic factor for survival
in patients with severe-to-critical coronavirus disease (COVID-19), but the clinical correlation …