[HTML][HTML] New developments in exosomal lncRNAs in cardiovascular diseases

Z Yuan, W Huang - Frontiers in Cardiovascular Medicine, 2021 - frontiersin.org
Long non-coding RNAs (lncRNAs) are non-coding RNAs with lengths> 200 nt and are
involved in the occurrence and development of cardiovascular diseases (CVDs). Exosomes …

[HTML][HTML] Application of fibrin associated with photobiomodulation as a promising strategy to improve regeneration in tissue engineering: A systematic review

CHB Reis, DV Buchaim, AC Ortiz, SOM Fideles… - Polymers, 2022 - mdpi.com
Fibrin, derived from proteins involved in blood clotting (fibrinogen and thrombin), is a
biopolymer with different applications in the health area since it has hemostasis …

Exosome-based cell-free therapy in regenerative medicine for myocardial repair

KH Haider, M Najimi - Handbook of stem cell therapy, 2022 - Springer
Exosomes in cardiovascular theranostics are gaining popularity due to their immense
diagnostic and therapeutic potential generally ascribed to their specific payload and …

[HTML][HTML] Efficacy of stem cell therapy in large animal models of ischemic cardiomyopathies: A systematic review and meta-analysis

D La Mantia, C Bernardini, A Zannoni, R Salaroli… - Animals, 2022 - mdpi.com
Simple Summary The present work focuses on stem-cell assessment as a therapeutic
approach on cardiovascular diseases, both in terms of safety and efficacy. In particular, this …

[HTML][HTML] Follistatin-like 1 promotes proliferation of matured human hypoxic iPSC-cardiomyocytes and is secreted by cardiac fibroblasts

MC Peters, S Di Martino, T Boelens, J Qin… - … Therapy-Methods & …, 2022 - cell.com
The human heart has limited regenerative capacity. Therefore, patients often progress to
heart failure after ischemic injury, despite advances in reperfusion therapies generally …

Promising roles of non-exosomal and exosomal non-coding RNAs in the regulatory mechanism and as diagnostic biomarkers in myocardial infarction

J Li, H Ma, X Wu, G Sun, P Yang, Y Peng… - Journal of Zhejiang …, 2023 - Springer
Non-exosomal non-coding RNAs (non-exo-ncRNAs) and exosomal ncRNAs (exo-ncRNAs)
have been associated with the pathological development of myocardial infarction (MI) …

[HTML][HTML] The epicardial delivery of cardiosphere derived cells or their extracellular vesicles is safe but of limited value in experimental infarction

V Crisóstomo, C Baéz-Diaz, V Blanco-Blázquez… - Scientific Reports, 2021 - nature.com
The epicardial administration of therapeutics via the pericardial sac offers an attractive route,
since it is minimally invasive and carries no risks of coronary embolization. The aim of this …

[HTML][HTML] Large Animal Models in Cardiovascular Research

H Osada, K Murata, H Masumoto - Animal Models and …, 2022 - intechopen.com
Studies of not only preclinical cardiovascular research but also those of life science,
medical, and pharmacological fields commonly utilize small animal models. However, for the …

[图书][B] Animal Models and Experimental Research in Medicine

M Karapehlivan, V Gelen, A Kükürt - 2023 - books.google.com
The use of experimental animals is quite common in medical research, especially for
pharmaceutical developments and molecular pathway studies. Considering the effects of …

Visualization of cardiac uptake of bone marrow mesenchymal stem cell‐derived extracellular vesicles after intramyocardial or intravenous injection in murine …

CM Xu, SA Sabe, R Brinck‐Teixeira… - Physiological …, 2023 - Wiley Online Library
In animal models, human bone marrow mesenchymal stem cell‐derived extracellular
vesicles (MSC‐EV) have been found to have beneficial effects in cardiovascular disease …