On the importance of cotranscriptional RNA structure formation

D Lai, JR Proctor, IM Meyer - Rna, 2013 - rnajournal.cshlp.org
The expression of genes, both coding and noncoding, can be significantly influenced by
RNA structural features of their corresponding transcripts. There is by now mounting …

Antibiotic-free selection in biotherapeutics: now and forever

C Mignon, R Sodoyer, B Werle - Pathogens, 2015 - mdpi.com
The continuously improving sophistication of molecular engineering techniques gives
access to novel classes of bio-therapeutics and new challenges for their production in full …

Distinct type I and type II toxin-antitoxin modules control Salmonella lifestyle inside eukaryotic cells

D Lobato-Márquez, I Moreno-Córdoba, V Figueroa… - Scientific reports, 2015 - nature.com
Toxin-antitoxin (TA) modules contribute to the generation of non-growing cells in response
to stress. These modules abound in bacterial pathogens although the bases for this …

Cross-regulations between bacterial toxin–antitoxin systems: evidence of an interconnected regulatory network?

C Riffaud, ML Pinel-Marie, B Felden - Trends in microbiology, 2020 - cell.com
Toxin–antitoxin (TA) systems are ubiquitous among bacteria and include stable toxins
whose toxicity can be counteracted by RNA or protein antitoxins. They are involved in …

Profiling the intragenic toxicity determinants of toxin–antitoxin systems: revisiting hok/Sok regulation

A Le Rhun, NJ Tourasse, S Bonabal, I Iost… - Nucleic Acids …, 2023 - academic.oup.com
Type I toxin–antitoxin systems (T1TAs) are extremely potent bacterial killing systems difficult
to characterize using classical approaches. To assess the killing capability of type I toxins …

Functionality and cross-regulation of the four SprG/SprF type I toxin–antitoxin systems in Staphylococcus aureus

C Riffaud, ML Pinel-Marie, G Pascreau… - Nucleic acids …, 2019 - academic.oup.com
Toxin–antitoxin (TA) systems are ubiquitous among bacteria, frequently expressed in
multiple copies, and important for functions such as antibiotic resistance and persistence …

Guidelines for designing the antithetic feedback motif

AA Baetica, YP Leong, RM Murray - Physical Biology, 2020 - iopscience.iop.org
Integral feedback control is commonly used in mechanical and electrical systems to achieve
zero steady-state error following an external disturbance. Equivalently, in biological systems …

Bioinformatics of prokaryotic RNAs

R Backofen, F Amman, F Costa, S Findeiß… - RNA biology, 2014 - Taylor & Francis
The genome of most prokaryotes gives rise to surprisingly complex transcriptomes,
comprising not only protein-coding mRNAs, often organized as operons, but also harbors …

Deciphering the Universe of RNA Structures and trans RNA–RNA Interactions of Transcriptomes In Vivo: From Experimental Protocols to Computational Analyses

SR Stefanov, IM Meyer - Systems Biology, 2018 - Springer
The last few years have seen an explosion of experimental and computational methods for
investigating RNA structures of entire transcriptomes in vivo. Very recent experimental …

e-RNA: a collection of web servers for comparative RNA structure prediction and visualisation

D Lai, IM Meyer - Nucleic acids research, 2014 - academic.oup.com
Abstract e-RNA offers a free and open-access collection of five published RNA sequence
analysis tools, each solving specific problems not readily addressed by other available tools …