Applications of OR/ECD/VCD to the structure elucidation of natural products

A Mándi, T Kurtán - Natural product reports, 2019 - pubs.rsc.org
Covering: 2012 to 2018 The principles and applicability of optical rotation, and electronic
and vibrational circular dichroism aided by quantum chemical calculations are presented to …

Fungal pigments and their roles associated with human health

L Lin, J Xu - Journal of Fungi, 2020 - mdpi.com
Fungi can produce myriad secondary metabolites, including pigments. Some of these
pigments play a positive role in human welfare while others are detrimental. This paper …

Recent advances in the chemistry and biology of azaphilones

C Chen, H Tao, W Chen, B Yang, X Zhou, X Luo… - RSC advances, 2020 - pubs.rsc.org
Azaphilones have continuously aroused considerable attention owing to their structural
diversity and significant biological activities recently. This review attempts to give a …

Deciphering the evolution of flavin-dependent monooxygenase stereoselectivity using ancestral sequence reconstruction

CH Chiang, T Wymore… - Proceedings of the …, 2023 - National Acad Sciences
Controlling the selectivity of a reaction is critical for target-oriented synthesis. Accessing
complementary selectivity profiles enables divergent synthetic strategies, but is challenging …

The Natural Products and Extracts: Anti‐Triple‐Negative Breast Cancer in Vitro

H Chen, J Yang, Y Yang, J Zhang, Y Xu… - Chemistry & …, 2021 - Wiley Online Library
Triple‐negative breast cancer (TNBC) makes up 15% to 20% of all breast cancer (BC)
cases, and represents one of the most challenging malignancies to treat. For many years …

Targeting the DNA damage response (DDR) by natural compounds

J van Stuijvenberg, P Proksch, G Fritz - Bioorganic & medicinal chemistry, 2020 - Elsevier
Natural compounds (NC) are an important source of anticancer drugs. The genomic DNA of
tumor cells is a major target of conventional anticancer therapeutics (cAT). DNA damage …

Eurochevalierines AI, Sesquiterpene Alkaloid Hybrids with Anti-Triple Negative Breast Cancer Activity from Penicillium sp. HZ-5

Y Zhang, Q Li, J Zhang, M Chen, X Li… - Journal of Agricultural …, 2024 - ACS Publications
Nine new sesquiterpene alkaloids, eurochevalierines A–I (1–9), were separated from the
rice cultures of the endophytic fungus Penicillium sp. HZ-5 originated from the fresh leaf of …

Induction of Secondary Metabolite Biosynthesis by Deleting the Histone Deacetylase HdaA in the Marine-Derived Fungus Aspergillus terreus RA2905

YY Zheng, ZL Ma, JS Wu, CL Shao, GS Yao, CY Wang - Journal of Fungi, 2022 - mdpi.com
Aspergillus terreus is well-known for its ability to biosynthesize valuable pharmaceuticals as
well as structurally unique secondary metabolites. However, numerous promising cryptic …

Genome Assembly and Transcriptome Analysis of the Fungus Coniella diplodiella During Infection on Grapevine (Vitis vinifera L.)

R Liu, Y Wang, P Li, L Sun, J Jiang, X Fan… - Frontiers in …, 2021 - frontiersin.org
Grape white rot caused by Coniella diplodiella (Speg.) affects the production and quality of
grapevine in China and other grapevine-growing countries. Despite the importance of C …

Dereplication of Sclerotiorin-Like Azaphilones Produced by Penicillium meliponae Using LC-MS/MS Analysis and Molecular Networking

EG Peres, MP Souza, TF Sousa, CVA Silva… - Journal of the Brazilian …, 2023 - SciELO Brasil
Penicillium meliponae, a recently described and rare species, was isolated as an
endophytic fungus from the Amazonian plant Duguetia sthelechantha, and has been proven …