The interest in the liver dates back to ancient times when it was considered to be the seat of
life processes. The liver is indeed essential to life, not only due to its complex functions in …

The complex functions of the liver in biosynthesis, metabolism, clearance, and host defense
are tightly dependent on an adequate microcirculation. To guarantee hepatic homeostasis …

BACKGROUND: Before extended hepatectomy of five or more segments, the remnant liver
volume (RLV) is usually calculated as a ratio of RLV to total liver volume (RLV-TLV) and …

Liver transplantation has been identified as the most effective treatment for patients with end-
stage liver diseases. However, hepatic ischemia reperfusion injury (IRI) is associated with …

Background Orthotopic liver transplantation (OLT) is the best available option for early
hepatocellular carcinoma (HCC), although its application is limited by stringent selection …

Background Since the first success in an adult patient, living donor liver transplantation
(LDLT) has become an universally used procedure. Small-for-size syndrome (SFSS) is a …

In an attempt to more completely define the histopathologic features of the portal vein
hyperperfusion or small-for-size syndrome (PHP/SFSS), we strictly identified 5 PHP/SFSS …

Ischemia/reperfusion injury is an inevitable process during liver transplantation and can lead
to a high incidence of early allograft dysfunction and graft failure. The mechanism of hepatic …

Hepatocellular carcinoma recurrence occurs in 40–70% of patients after hepatic resection.
Despite the high frequency of hepatocellular cancer relapse, there is no established …

Tumor recurrence is the major obstacle for pushing the envelope of liver transplantation for
hepatocellular carcinoma (HCC) patients. The inflammatory cascades activated by acute …