Biosystem‐inspired engineering of nanozymes for biomedical applications

L Zhang, H Wang, X Qu - Advanced Materials, 2024 - Wiley Online Library
Nanozymes with intrinsic enzyme‐mimicking activities have shown great potential to
become surrogates of natural enzymes in many fields by virtue of their advantages of high …

Nanomaterial-based bioorthogonal nanozymes for biological applications

S Fedeli, J Im, S Gopalakrishnan, JL Elia… - Chemical Society …, 2021 - pubs.rsc.org
Bioorthogonal transformations are chemical reactions that use pathways which biological
processes do not access. Bioorthogonal chemistry provides new approaches for imaging …

Boosting Endogenous Copper (I) for Biologically Safe and Efficient Bioorthogonal Catalysis via Self-Adaptive Metal–Organic Frameworks

J Zhu, Y You, W Zhang, F Pu, J Ren… - Journal of the American …, 2023 - ACS Publications
As one of the most typical bioorthogonal reactions, the Cu (I)-catalyzed azide–alkyne 1, 3-
cycloaddition (CuAAC) reaction has received worldwide attention in intracellular …

A bimetallic metal–organic framework encapsulated with DNAzyme for intracellular drug synthesis and self‐sufficient gene therapy

Z Wang, J Niu, C Zhao, X Wang, J Ren… - Angewandte …, 2021 - Wiley Online Library
Although chemotherapy is one of the most widely used cancer treatments, there are serious
side effects, drug resistance, and secondary metastasis. To address these problems, herein …

Progress in polymer single-chain based hybrid nanoparticles

Y Shao, Z Yang - Progress in Polymer Science, 2022 - Elsevier
Precise control of molecular hierarchical organization has endowed biological systems with
unique functions, which inspires great efforts in the synthesis of artificial mimics. Polymeric …

Metal complexes for catalytic and photocatalytic reactions in living cells and organisms

H Madec, F Figueiredo, K Cariou, S Roland… - Chemical …, 2023 - pubs.rsc.org
The development of organometallic catalysis has greatly expanded the synthetic chemist
toolbox compared to only exploiting “classical” organic chemistry. Although more widely …

Functional DNA molecules enable selective and stimuli-responsive nanoparticles for biomedical applications

L Li, H Xing, J Zhang, Y Lu - Accounts of chemical research, 2019 - ACS Publications
Conspectus Nanoparticles (NPs) have enormous potential to improve disease diagnosis
and treatment due to their intrinsic electronic, optical, magnetic, mechanical, and …

Intramolecularly cross-linked polymers: from structure to function with applications as artificial antibodies and artificial enzymes

J Chen, ES Garcia, SC Zimmerman - Accounts of chemical …, 2020 - ACS Publications
Conspectus Cross-linking of polymers significantly alters their physical properties, greatly
expanding their everyday utility. Indeed, the polymeric networks resulting from linkages …

Intracellular catalysis with selected metal complexes and metallic nanoparticles: advances toward the development of catalytic metallodrugs

JJ Soldevila-Barreda, N Metzler-Nolte - Chemical reviews, 2019 - ACS Publications
Platinum-containing drugs (eg, cisplatin) are among the most frequently used
chemotherapeutic agents. Their tremendous success has spurred research and …

A biocompatible heterogeneous MOF–Cu catalyst for in vivo drug synthesis in targeted subcellular organelles

F Wang, Y Zhang, Z Liu, Z Du, L Zhang… - Angewandte Chemie …, 2019 - Wiley Online Library
As a typical bioorthogonal reaction, the copper‐catalyzed azide–alkyne cycloaddition
(CuAAC) has been used for drug design and synthesis. However, for localized drug …