The discovery of the Sry gene in 1990 triggered a revolution in our understanding of sex
determination. More recently, advances in non-model organisms have been fuelled by the …

Biological differences between men and women contribute to many sex-specific illnesses
and disorders. Historically, it was argued that such differences were largely, if not …

Drawing on the latest research from around the world, Life of Marsupials explores this
unusual group of mammals covering the extraordinary diversity of forms around the world …

The first half of this review examines the boundary between endocrinology and embryonic
development, with the aim of highlighting the way hormones and signaling systems regulate …

Background We present the genome sequence of the tammar wallaby, Macropus eugenii,
which is a member of the kangaroo family and the first representative of the iconic hopping …

Mammalian sex determination (male versus female) is largely controlled by genes, whereas
sex differentiation (development of reproductive structures) is largely controlled by …

Abstract Cytochrome P450 17A1 (CYP17A1) is a critical steroidogenic enzyme, essential for
producing glucocorticoids and sex hormones. This review discusses the complex activity of …

Marsupials exhibit unique biological features that provide fascinating insights into many
aspects of mammalian development. These include their distinctive mode of reproduction …

Differentiation of the bipotential gonadal primordium into ovaries and testes is a common
process among vertebrate species. While vertebrate ovaries eventually share the same …

Abstract The Wolffian ducts (WDs) are the progenitors of the epididymis, vas deferens and
seminal vesicles. They form initially as nephric ducts that acquire connection to the …