Colorectal cancer (CRC) risk is predominantly driven by environmental factors, in particular
diet. A high intake of dietary fat has been implicated as a risk factor inducing the formation of …

Lactic acid bacteria (LAB), a group of Gram-positive microorganisms naturally occurring in
fermented food products and used as probiotics, have been gaining the interest of …

Increased levels of intestinal bile acids (BAs) are a risk factor for colorectal cancer (CRC).
Here, we show that the convergence of dietary factors (high-fat diet) and dysregulated WNT …

Metabolism is one of the strongest drivers of interkingdom interactions—including those
between microorganisms and their multicellular hosts. Traditionally thought to fuel energy …

who volunteer may be more representative of moderate and non-drinkers in the underlying
population. Thus the low risk of stroke in the heavy drinkers who volunteer for the study …

Colorectal carcinoma (CRC) is one of the most frequently diagnosed carcinomas and one of
the leading causes of cancer-related death worldwide. Metabolic reprogramming, a hallmark …

In the United States in the period 1973–1997, the incidence and mortality due to large bowel
cancer was higher in blacks than in other ethnic groups. The incidence in blacks in the …

PURPOSE: The mucosa of the small intestine encompasses about 90% of the luminal
surface area of the digestive system, but only 2% of the total annual gastrointestinal cancer …

The human gastrointestinal tract harbors a complex and abundant microbial community that
can reach levels as high as 10 13–10 14 microorganisms in the colon. These …

With the use of molecular techniques, numerous studies have evaluated the composition of
the intestinal microbiota in health and disease. However, it is of major interest to supplement …