Background We recently demonstrated that elexacaftor/tezacaftor/ivacaftor (ETI) improves
the lung clearance index (LCI) and abnormalities in lung morphology detected by magnetic …

Background With improvement in supportive therapies and the introduction of cystic fibrosis
transmembrane conductance regulator (CFTR)-modulator treatment in patients with cystic …

Lung function has traditionally been evaluated by spirometry, which measures changes in
flows and volumes during a forced expiratory maneuver. Forced expiratory volume in 1 …

Objectives In patients with congenital diaphragmatic hernia (CDH) the exact functional
outcome of the affected lung side is still unknown, mainly due to the lack of spatially resolved …

Background: Many children undergo allogeneic hematopoietic stem cell transplantation
(HSCT) for the treatment of malignant and nonmalignant conditions. Unfortunately …

Introduction No data are available on the values and role of lung clearance index (LCI) in
cystic fibrosis (CF) Screen Positive Inconclusive Diagnosis (CFSPID) progressed to CF …

Since the finding and correction of an error in previous spiroware software versions
commonly used with the Exhalyzer D for multiple-breath washout (MBW) analysis, there has …

Bronchiolitis obliterans syndrome (BOS) is a severe complication following hemopoietic
stem cell transplantation (HSCT) and is often undetected until there is significant …

Background The long-term consequences of prematurity are often not sufficiently
recognized. To address this gap, a prospective cohort study, which is a continuation of the …

The forced expiratory volume in one second (FEV1) is regularly used for the follow-up of
patients with non-cystic fibrosis bronchiectasis (nCF-BE). The lung clearance index (LCI) …