Non-coding RNAs (ncRNAs) are a heterogeneous group of transcripts that, by definition, are
not translated into proteins. Since their discovery, ncRNAs have emerged as important …

Resolution is an active and highly coordinated process that occurs in response to
inflammation to limit tissue damage and promote repair. When the resolution program fails …

Oxidized phospholipids (OxPL) are key mediators of the pro-atherosclerotic effects of
oxidized lipoproteins. They are particularly important for the pathogenicity of lipoprotein …

Impaired angiogenesis in diabetes is a key process contributing to ischemic diseases such
as peripheral arterial disease. Epigenetic mechanisms, including those mediated by long …

Background: Activation of vascular smooth muscle cell (VSMC) inflammation is vital to
initiate vascular disease. The role of human-specific long noncoding RNAs in VSMC …

Background: Coronary artery disease (CAD) is the leading cause of death worldwide.
Recent meta-analyses of genome-wide association studies have identified over 175 loci …

Abstract Lipoprotein (a)[Lp (a)], a distinct lipoprotein class, has become a major focus for
cardiovascular research. This review is written in light of the recent guideline and consensus …

BACKGROUND: The ADAMTS7 locus was genome-wide significantly associated with
coronary artery disease. Lack of the ECM (extracellular matrix) protease ADAMTS-7 (A …

Ischemic stroke is a detrimental neurological disease characterized by an irreversible infarct
core surrounded by an ischemic penumbra, a salvageable region of brain tissue. Unique …

In healthy vessels, endothelial cells maintain a stable, differentiated, and growth-arrested
phenotype for years. Upon injury, a rapid phenotypic switch facilitates proliferation to restore …