Dendritic cells, macrophages and B cells are regarded as the classical antigen-presenting
cells of the immune system. However, in recent years, there has been a rapid increase in the …

Eosinophils have been traditionally perceived as terminally differentiated cytotoxic effector
cells. Recent studies have profoundly altered this simplistic view of eosinophils and their …

The enigmatic eosinophil has emerged as an exciting component of the immune system,
involved in a plethora of homeostatic and inflammatory responses. Substantial progress has …

Eosinophilia is a central feature of the host response to helminth infection. Larval stages of
parasitic worms are killed in vitro by eosinophils in the presence of specific antibodies or …

Eosinophils are leukocytes resident in mucosal tissues. During T‐helper 2 (Th2)‐type
inflammation, eosinophils are recruited from bone marrow and blood to the sites of immune …

Metazoan parasites typically induce a type 2 immune response, characterized by T helper 2
(Th2) cells that produce the cytokines IL-4, IL-5 and IL-13 among others. The type 2 …

In this review, we aim to put in perspective the biology of a multifunctional leukocyte, the
eosinophil, by placing it in the context of innate and adaptive immune responses …

Eosinophils are innate immune leukocytes found in relatively low numbers within the blood.
Terminal effector functions of eosinophils, deriving from their capacity to release their …

Surprisingly, the role (s) of eosinophils in health and disease is often summarized by
clinicians and basic research scientists as a pervasive consensus opinion first learned in …

Asthma is a common, disabling inflammatory respiratory disease that has increased in
frequency and severity in developed nations. We review studies of murine allergic airway …