Red meat and processed meat consumption has been hypothesized to increase risk of
cancer, but the evidence is inconsistent. We performed a systematic review and meta …

Vitamins B9 (folate) and B12 are essential water-soluble vitamins that play a crucial role in
the maintenance of one-carbon metabolism: a set of interconnected biochemical pathways …

The essential amino acid, methionine, is important for cancer cell growth and metabolism. A
growing body of evidence indicates that methionine restriction inhibits cancer cell growth …

Methionine is an essential amino acid with many key roles in mammalian metabolism such
as protein synthesis, methylation of DNA and polyamine synthesis. Restriction of methionine …

Introduction: All tested cancer cell types are methionine dependent in that the cells arrest
and eventually die when deprived of methionine, a condition that is generally nontoxic to …

Purpose: Ionizing radiation (IR) is a ubiquitous environmental stressor with genotoxic and
epigenotoxic capabilities. Terrestrial IR, predominantly a low-linear energy transfer (LET) …

Autosomal dominant polycystic kidney disease (ADPKD) is a common monogenic disorder
marked by numerous progressively enlarging kidney cysts. Mettl3, a methyltransferase that …

Biopharmaceuticals is a rapidly emerging field that explores and employs biological
organisms and their products for therapeutic applications. Enzymes are remarkable …

Amino acid deprivation therapy (AADT) is emerging as a promising strategy for the
development of novel therapeutics against cancer. This biological therapy relies upon the …

Interest in studying cancer metabolism has risen in recent years, as it has become evident
that the relationship between cancer and metabolic pathways could reveal novel biomarkers …