Does the Leishmania major paradigm of pathogenesis and protection hold for New World cutaneous leishmaniases or the visceral disease?

D McMahon‐Pratt, J Alexander - Immunological reviews, 2004 - Wiley Online Library
Parasitic protozoa of the genus Leishmania have provided a useful perspective for
immunologists in terms of host defense mechanisms critical for the resolution of infection …

Vaccine candidates for leishmaniasis: a review

R Nagill, S Kaur - International immunopharmacology, 2011 - Elsevier
Leishmaniasis is a diverse group of clinical syndromes caused by protozoan parasites of the
genus Leishmania. The clinical manifestation of the disease varies from self-limiting …

Protective immunity against challenge with Leishmania (Leishmania) chagasi in beagle dogs vaccinated with recombinant A2 protein

AP Fernandes, MMS Costa, EAF Coelho… - Vaccine, 2008 - Elsevier
In this study, we investigated in dogs the immunogenicity and protective immunity against
Leishmania (Leishmania) chagasi infection induced by vaccination with a formulation …

[HTML][HTML] Vaccination in leishmaniasis: a review article

L Abdellahi, F Iraji, A Mahmoudabadi… - Iranian Biomedical …, 2022 - ncbi.nlm.nih.gov
Leishmaniasis is caused by protozoan Leishmania parasites that are transmitted through
female sandfly bites. The disease is predominantly endemic to the tropics and semi-tropics …

Field randomized trial to evaluate the efficacy of the Leish-Tec® vaccine against canine visceral leishmaniasis in an endemic area of Brazil

S Regina-Silva, AMLT Feres, JC França-Silva, ES Dias… - Vaccine, 2016 - Elsevier
Background A canine vaccine remains a promising approach for effective control of visceral
leishmaniasis (VL), given its complex epidemiology in areas where zoonotic VL is prevalent …

Identification of Proteins in Promastigote and Amastigote-like Leishmania Using an Immunoproteomic Approach

VTS Coelho, JS Oliveira, DG Valadares… - PLoS Neglected …, 2012 - journals.plos.org
Background The present study aims to identify antigens in protein extracts of promastigote
and amastigote-like Leishmania (Leishmania) chagasi syn. L.(L.) infantum recognized by …

A recombinant chimeric protein-based vaccine containing T-cell epitopes from amastigote proteins and combined with distinct adjuvants, induces immunogenicity and …

DP Lage, DL Vale, FP Linhares, CS Freitas… - Vaccines, 2022 - mdpi.com
Currently, there is no licensed vaccine to protect against human visceral leishmaniasis (VL),
a potentially fatal disease caused by infection with Leishmania parasites. In the current …

Antileishmanial activity and cytotoxicity of Brazilian plants

TG Ribeiro, MA Chávez-Fumagalli, DG Valadares… - Experimental …, 2014 - Elsevier
Leishmaniasis is a major public health problem, and the alarming spread of parasite
resistance has increased the importance of discovering new therapeutic products. The …

Leishmanicidal activity of the Agaricus blazei Murill in different Leishmania species

DG Valadares, MC Duarte, JS Oliveira… - Parasitology …, 2011 - Elsevier
Leishmaniasis is a major public health problem, and the alarming spread of parasite
resistance underlines the importance of discovering new therapeutic products. The present …

Novel targeting using nanoparticles: an approach to the development of an effective anti-leishmanial drug-delivery system

TG Ribeiro, MA Chávez-Fumagalli… - International journal …, 2014 - Taylor & Francis
The study reported here aimed to develop an optimized nanoparticle delivery system for
amphotericin B (AmpB) using a polyelectrolyte complexation technique. For this, two …