[HTML][HTML] ACE2-independent alternative receptors for SARS-CoV-2

S Lim, M Zhang, TL Chang - Viruses, 2022 - mdpi.com
Severe acute respiratory syndrome-related coronavirus (SARS-CoV-2), the causative agent
of coronavirus disease 2019 (COVID-19), is highly contagious and remains a major public …

[HTML][HTML] Immune response to dengue and Zika

A Elong Ngono, S Shresta - Annual review of immunology, 2018 - annualreviews.org
Flaviviruses such as dengue (DENV), yellow fever (YFV), West Nile (WNV), and Zika (ZIKV)
are human pathogens of global significance. In particular, DENV causes the most prevalent …

Zika virus infection damages the testes in mice

J Govero, P Esakky, SM Scheaffer, E Fernandez… - Nature, 2016 - nature.com
Infection of pregnant women with Zika virus (ZIKV) can cause congenital malformations
including microcephaly, which has focused global attention on this emerging pathogen. In …

Zika virus cell tropism in the developing human brain and inhibition by azithromycin

H Retallack, E Di Lullo, C Arias… - Proceedings of the …, 2016 - National Acad Sciences
The rapid spread of Zika virus (ZIKV) and its association with abnormal brain development
constitute a global health emergency. Congenital ZIKV infection produces a range of mild to …

[HTML][HTML] Recent African strains of Zika virus display higher transmissibility and fetal pathogenicity than Asian strains

F Aubry, S Jacobs, M Darmuzey, S Lequime… - Nature …, 2021 - nature.com
The global emergence of Zika virus (ZIKV) revealed the unprecedented ability for a mosquito-
borne virus to cause congenital birth defects. A puzzling aspect of ZIKV emergence is that all …

[HTML][HTML] Zika virus antagonizes type I interferon responses during infection of human dendritic cells

JR Bowen, KM Quicke, MS Maddur, JT O'Neal… - PLoS …, 2017 - journals.plos.org
Zika virus (ZIKV) is an emerging mosquito-borne flavivirus that is causally linked to severe
neonatal birth defects, including microcephaly, and is associated with Guillain-Barre …

Host-directed antiviral therapy

N Kumar, S Sharma, R Kumar, BN Tripathi… - Clinical microbiology …, 2020 - Am Soc Microbiol
Antiviral drugs have traditionally been developed by directly targeting essential viral
components. However, this strategy often fails due to the rapid generation of drug-resistant …

[HTML][HTML] Thrombocytopenia in virus infections

M Raadsen, J Du Toit, T Langerak… - Journal of clinical …, 2021 - mdpi.com
Thrombocytopenia, which signifies a low platelet count usually below 150× 109/L, is a
common finding following or during many viral infections. In clinical medicine, mild …

Antiviral strategies targeting host factors and mechanisms obliging+ ssRNA viral pathogens

S Mahajan, S Choudhary, P Kumar, S Tomar - Bioorganic & Medicinal …, 2021 - Elsevier
The ongoing COVID-19 pandemic, periodic recurrence of viral infections, and the
emergence of challenging variants has created an urgent need of alternative therapeutic …

The antigenic structure of Zika virus and its relation to other flaviviruses: implications for infection and immunoprophylaxis

FX Heinz, K Stiasny - Microbiology and Molecular Biology …, 2017 - Am Soc Microbiol
Zika virus was discovered∼ 70 years ago in Uganda and maintained a low profile as a
human disease agent in Africa and Asia. Only recently has it caused explosive outbreaks in …