[HTML][HTML] Preparation of functional coating on magnesium alloy with hydrophilic polymers and bioactive peptides for improved corrosion resistance and biocompatibility

L Bai, Y Wang, L Chen, J Wang, J Li, S Zhu… - Journal of Magnesium …, 2022 - Elsevier
Biodegradable magnesium alloy stents (MAS) have great potential in the treatment of
cardiovascular diseases. However, too fast degradation and the poor biocompatibility are …

Fucoidan/collagen composite coating on magnesium alloy for better corrosion resistance and pro-endothelialization potential

Y Wang, Y Zhao, X Wang, Y Xie, L Bai… - International Journal of …, 2024 - Elsevier
Magnesium alloy stents (MAS) have broad application prospects in the treatment of
cardiovascular diseases. However, poor corrosion resistance and biocompatibility greatly …

Contemporary medicinal-chemistry strategies for discovery of blood coagulation factor Xa inhibitors

X Hao, X Zuo, D Kang, J Zhang, Y Song… - Expert opinion on …, 2019 - Taylor & Francis
Introduction: Thrombosis is a common causal pathology for stroke, acute coronary syndrome
and venous thromboembolism disorders, which are the leading cause of death worldwide …

Proteome analysis in PAM cells reveals that African swine fever virus can regulate the level of intracellular polyamines to facilitate its own replication through ARG1

Q Ai, X Lin, H Xie, B Li, M Liao, H Fan - Viruses, 2021 - mdpi.com
In 2018, African swine fever broke out in China, and the death rate after infection was close
to 100%. There is no effective and safe vaccine in the world. In order to better characterize …

Direct Oral FXa Inhibitors Binding to Human Serum Albumin: Spectroscopic, Calorimetric, and Computational Studies

N Mariño-Ocampo, DF Rodríguez… - International Journal of …, 2023 - mdpi.com
Direct FXa inhibitors are an important class of bioactive molecules (rivaroxaban, apixaban,
edoxaban, and betrixaban) applied for thromboprophylaxis in diverse cardiovascular …

Evaluation procoagulant activity and mechanism of astragalin

C Li, M Hu, S Jiang, Z Liang, J Wang, Z Liu, HMD Wang… - Molecules, 2020 - mdpi.com
Astragalin, isolated from flowers of Rosa chinensis Jacq., is a kind of flavonoid, with anti-
inflammatory, antioxidant, antiviral, analgesic, antibacterial, antiallergic, and antihepatotoxic …

Chemical Constituents and Coagulation Activity of Amygdalus persica L. Flowers

J Zhang, W Zhang, Z Yin, B Yang… - Natural Product …, 2021 - journals.sagepub.com
The ethyl acetate extract of Amygdalus persica L. flowers (family Rosaceae) was
fractionated by silica gel and Sephadex LH-20 column chromatography, and, after …

Probing factor xa protein–ligand interactions: Accurate free energy calculations and experimental validations of two series of high-affinity ligands

MI Fernandez-Bachiller, S Hwang… - Journal of Medicinal …, 2022 - ACS Publications
The accurate prediction of protein–ligand binding affinity belongs to one of the central goals
in computer-based drug design. Molecular dynamics (MD)-based free energy calculations …

Dirofilaria immitis possesses molecules with anticoagulant properties in its excretory/secretory antigens

A Diosdado, F Simón, R Morchón, J González-Miguel - Parasitology, 2020 - cambridge.org
Dirofilaria immitis is a parasitic nematode that survives in the circulatory system of suitable
hosts for many years, causing the most severe thromboembolisms when simultaneous death …

Preparation of an anticoagulant polyethersulfone membrane by immobilizing FXa inhibitors with a polydopamine coating

C Wang, D Jiang, H Ge, J Ning, X Li… - Journal of Biomaterials …, 2024 - Taylor & Francis
Anticoagulation treatment for patients with high bleeding risk during hemodialysis is
challenging. Contact between the dialysis membrane and the blood leads to protein …