Harnessing polymer-derived drug delivery systems for combating inflammatory bowel disease

Y Pu, X Fan, Z Zhang, Z Guo, Q Pan, W Gao… - Journal of Controlled …, 2023 - Elsevier
The inflammatory bowel disease (IBD) is incurable, chronic, recrudescent disorders in the
inflamed intestines. Current clinic treatments are challenged by systemic exposure-induced …

Nano-enabled colorectal cancer therapy

Q Pan, X Fan, L Xie, D Wu, R Liu, W Gao, K Luo… - Journal of Controlled …, 2023 - Elsevier
Colorectal cancer (CRC), one of the most common and deadliest diseases worldwide, poses
a great health threat and social burden. The clinical treatments of CRC encompassing …

Microenvironment responsive pod-structured astaxanthin nanocarrier for ameliorating inflammatory bowel disease

J Wang, Y Chen, L Han, S Xia, X Zhang, P Xue… - Chinese Chemical …, 2024 - Elsevier
Anti-inflammatory drugs targeting inflammatory bowel disease (IBD) have attracted
considerable attention but still face low therapeutic outcomes and frequent side effects …

Scalable fabrication of uniform nanoparticles for the efficient co-encapsulation of curcumin and procyanidins driven by multiple interactions

F Feng, J Gao, L Chen, S Xiao, G Huang - Food Hydrocolloids, 2023 - Elsevier
The co-delivery of curcumin (CUR) with other polyphenol bioactives often has synergistic
benefits. However, conventional co-encapsulation carriers formed by precipitation frequently …

Light-assisted “nano-neutrophils” with high drug loading for targeted cancer therapy

D Fan, S Wang, R Huang, X Liu, H He… - International Journal of …, 2023 - Taylor & Francis
Background Nanomedicine presents a promising alternative for cancer treatment owing to
its outstanding features. However, the therapeutic outcome is still severely compromised by …

[HTML][HTML] Encapsulation of polyphenolic compounds based on hemicelluloses to enhance treatment of inflammatory bowel diseases and colorectal cancer

M Caban, U Lewandowska - Molecules, 2023 - mdpi.com
Inflammatory bowel diseases (IBD) and colorectal cancer (CRC) are difficult to cure, and
available treatment is associated with troubling side effects. In addition, current therapies …

Tannic Acid-Modified Decellularized Tendon Scaffold with Antioxidant and Anti-Inflammatory Activities for Tendon Regeneration

LL Zhao, JJ Luo, J Cui, X Li, RN Hu… - … Applied Materials & …, 2024 - ACS Publications
Tendon regeneration is greatly influenced by the oxidant and the inflammatory
microenvironment. Persistent inflammation during the tendon repair can cause matrix …

Advances of natural polyphenol based anti-oxidant nanomaterials for efficient treatment of inflammatory bowel disease

L Wang, Y Yang, C Xu, L Zhu, G Chen, H Yang… - Authorea …, 2023 - techrxiv.org
Excessive generation of reactive oxygen species (ROS) resulting in oxidative stress and
plays a crucial role in the progression of inflammatory bowel disease (IBD), which may in …