Abstract Streptococcus pyogenes (Group A Streptococcus; GAS) is exquisitely adapted to
the human host, resulting in asymptomatic infection, pharyngitis, pyoderma, scarlet fever or …

Streptococcus pyogenes, also known as Group A Streptococcus (GAS), is a Gram-positive
human-exclusive pathogen, responsible for more than 500 000 deaths annually worldwide …

Increases in invasive group A streptococcal (iGAS) infection and associated deaths,
particularly in children, above seasonally expected levels are being seen this season (772 …

A highly virulent sub-lineage of the Streptococcus pyogenes M1 clone has been rapidly
expanding throughout Denmark since late 2022 and now accounts for 30% of the new …

A new variant of Streptococcus pyogenes serotype M1 (designated 'M1UK') has been
reported in the United Kingdom, linked with seasonal scarlet fever surges, marked increase …

Since autumn 2022, observed numbers of paediatric invasive group A Streptococcus
infections in Portugal (n= 89) were higher than in pre-COVID-19 seasons. Between …

Many European countries have recently reported upsurges in invasive group A
Streptococcus (iGAS) infections, mainly caused by emm1 Streptococcus pyogenes …

The age of children with pleural empyema with confirmed GAS infection ranged from 10
months to 11 years (median 3 [IQR 1· 6–5] years); nine (56%) of the 16 cases were in boys …

Increasing reports of invasive Streptococcus pyogenes infections mandate surveillance for
toxigenic lineage M1 UK. An allele-specific PCR was developed to distinguish M1 UK from …

Since the beginning of December 2022, unusually high numbers of cases and deaths
among children have been reported across the United Kingdom (UK) and other regional …