Prevalence of diarylprolinol silyl ethers as catalysts in total synthesis and patents

GJ Reyes-Rodríguez, NM Rezayee… - Chemical …, 2019 - ACS Publications
Diarylprolinol silyl ethers are among the most utilized stereoselective organocatalysts for the
construction of complex molecules. With their debut in 2005, these catalysts have been …

Recent applications of asymmetric organocatalytic annulation reactions in natural product synthesis

N Wang, Z Wu, J Wang, N Ullah, Y Lu - Chemical Society Reviews, 2021 - pubs.rsc.org
The past two decades have witnessed remarkable growth of asymmetric organocatalysis,
which is now a firmly established synthetic tool, serving as a powerful platform for the …

Influenza-existing drugs and treatment prospects

A Sarker, Z Gu, L Mao, Y Ge, D Hou, J Fang… - European Journal of …, 2022 - Elsevier
Influenza is a century-old disease that continues to baffle humans by its frequently changing
nature, seasonal epidemics, and occasional pandemics. Approximately 9% of the world's …

Recent progress in the Horner-Wadsworth-Emmons reaction

JA Bisceglia, LR Orelli - Current Organic Chemistry, 2015 - ingentaconnect.com
The Horner-Wadsworth-Emmons reaction is one of the most reliable and widespread
synthetic tools for the stereocontrolled construction of ethylenic bonds. The versatility of the …

Advances in the asymmetric total synthesis of natural products using chiral secondary amine catalyzed reactions of α, β-unsaturated aldehydes

Z Wang - Molecules, 2019 - mdpi.com
Chirality is one of the most important attributes for its presence in a vast majority of bioactive
natural products and pharmaceuticals. Asymmetric organocatalysis methods have emerged …

Triacetic acid lactone as a bioprivileged molecule in organic synthesis

DL Obydennov, AI El-Tantawy… - Mendeleev …, 2019 - Elsevier
Major methods for the preparation of triacetic acid lactone and its application as a
bioprivileged compound in the synthesis of various valuable materials are summarized. Due …

Total synthesis of homodimericin A

J Feng, X Lei, Z Guo, Y Tang - Angewandte Chemie, 2017 - Wiley Online Library
We report the concise total synthesis of homodimericin A (1), a recently identified fungal
metabolite bearing an unprecedented molecular architecture. The success of the approach …

Organocatalysis in the Synthesis of Natural Products: Recent Developments in Aldol and Mannich Reactions, and 1, 4-Conjugated Additions

E Dibello, D Gamenara, G Seoane - Current Organocatalysis, 2015 - ingentaconnect.com
The use of organocatalysis has simplified and increased the potential of synthetic
approaches to natural products. Different aspects, regarding applications and even …

Sustainable Triacetic Acid Lactone Production from Sugarcane by Fermentation and Crystallization

S Bhagwat, M Dell'Anna, Y Li, M Cao, E Brace… - 2024 - chemrxiv.org
There is a pressing need to replace crude oil with renewable feedstocks such as sugarcane
to manufacture fuels and chemicals. Triacetic acid lactone (TAL) is a bioproduct of particular …

Lignan Chirality Roadmap A Scientific Art in Danger of Being Lost?

LB Davin, SGA Moinuddin, D Ferreira… - The Lignan …, 2022 - taylorfrancis.com
Plant natural products are frequently chiral, the word being derived from the Greek “chir” for
hand. Comprehensive phytochemical or natural product investigations of vascular plants …