Cryptococcosis is a globally distributed invasive fungal infection that is caused by species
within the genus Cryptococcus which presents substantial therapeutic challenges. Although …

Monocytes fundamentally contribute to immune surveillance and the inflammatory response
in immunoinflammatory diseases like atherosclerosis. Recruitment of these cells to the site …

Fracture repair is initiated by a multitude of immune cells and induction of an inflammatory
cascade. Alterations in the early healing response due to an aged adaptive immune system …

Cryptococcosis is caused by the fungal genus Cryptococcus. Cryptococcosis, predominantly
meningoencephalitis, emerged with the HIV pandemic, primarily afflicting HIV-infected …

Combination of passive targeting with active targeting is a promising approach to improve
the therapeutic efficacy of nanotherapy. However, most reported polymeric systems have …

Spinal cord injury results in destructive events that lead to tissue loss and functional
impairments. A hallmark of spinal cord injury is the robust and persistent presence of …

Tumor necrosis factor alpha (TNF-α) plays a critical role in the control of cryptococcal
infection, and its insufficiency promotes cryptococcal persistence. To explore the therapeutic …

Cryptococcus is an opportunistic fungal pathogen that can cause disseminated infection with
predominant central nervous system involvement in patients with compromised immunity …

Mannose receptor is considered as a hallmark of M2-oriented tumor-associated
macrophages (TAMs), but its utility in TAMs was rarely reported. Therefore, deoxymannose …

Cryptococcus neoformans is an opportunistic fungal pathogen that causes over 180,000
annual deaths in HIV/AIDS patients. Innate phagocytes in the lungs, such as dendritic cells …