Immunotherapy is a milestone in the treatment of poor-prognosis pediatric acute
lymphoblastic leukemia (ALL) and is expected to improve treatment outcomes and reduce …

Chimeric Antigen Receptor T (CAR-T) cell therapy has dramatically changed prognosis and
treatment of relapsed and refractory hematologic malignancies. Currently the 6 FDA …

Chimeric antigen receptor (CAR)-T cell therapy has revolutionized the management of
several life-threatening malignancies, often achieving durable sustained responses. The …

The use of chimeric antigen receptor T (CAR-T) cells is a significant therapeutic
improvement increasing the prognosis for patients with a variety of hematological …

Background This systematic review aimed to characterise the cognitive outcomes of patients
who received chimeric antigen receptor T-cell therapy. Methods A systematic search of the …

Immunotherapy with chimeric antigen receptor T (CAR-T) cell therapies has brought
substantial improvement in clinical outcomes in patients with relapsed/refractory B cell …

Polyphenols are one of the largest plant-derived natural product and they play an important
role in plants' defense as well as in human health and disease. A number of them are …

Variability or stability might have an impact on treatment success and toxicity of CD19 CAR T-
cells. We conducted a prospective observational study of 12 patients treated with …

Chimeric antigen receptor (CAR) T-cell therapy is associated with potentially severe
toxicities that create a substantial burden for patients. Patient-reported outcomes (PROs) …

Chimeric antigen receptor (CAR) T-cell therapy has been touted as a revolutionary
therapeutic breakthrough for certain cancers. The immune T cells can be genetically …