Arginine (L-arginine), is an amino acid involved in a number of biological processes,
including the biosynthesis of proteins, host immune response, urea cycle, and nitric oxide …

Despite the dynamic progress of modern medicine, oncological and cardiovascular
diseases (CVD) remain a severe economic burden worldwide. Therefore, the study of …

Cardiotoxicity is a major cause of high attrition rates among newly developed drugs.
Moreover, anti-cancer treatment-induced cardiotoxicity is one of the leading reasons of …

Purpose The current randomized, double-blind, placebo-controlled clinical trial addressed
the effects on penile erectile function of relatively high daily oral doses (6 g/day) of l-ARG for …

Background: Chemotherapy with doxorubicin and cyclophosphamide, although efficient for
treating breast cancer, is associated with cardiovascular complications. Recent studies seek …

The cardiotoxicity of pirarubicin (THP) seriously affects its clinical application, which cannot
be ignored. The antioxidant effect of schisandrin B (SchB) has been extensively reported in …

Introduction Anthracycline-based chemotherapy increases the risk of cancer therapeutics-
related cardiac dysfunction. Recently, evidences from in vitro experiments and animal …

While oncotherapy has made rapid progress in recent years, side effects of anti-cancer
drugs and treatments have also come to the fore. These side effects include cardiotoxicity …

Background Clinical or subclinical cardiotoxicity is a concern for cancer patients receiving
anthracycline-based chemotherapy. Carvedilol is promising for preventing anthracycline …

Arginine is the essential amino acid having potential therapeutic value. The amino acid can
be extracted from different natural resources. But they are not feasible due to efficient …