Publisher Summary This chapter discusses techniques for the preparation and
characterization of mitochondrial and submitochondrial fractions from liver and liver-derived …

Metabolism and mechanics are two key facets of structural and functional processes in cells,
such as growth, proliferation, homeostasis and regeneration. Their reciprocal regulation has …

The site of action of the antimalarial compound 2-[trans-4-(4'-chlorophenyl) cyclohexyl]-3-
hydroxy-1, 4-naphthoquinone (566C80), would appear to be the mitochondrial respiratory …

We have investigated the subcellular localization of the peripheral-type benzodiazepine
receptor in rat adrenal gland using the high affinity ligand 3H-labeled 1-(2-chlorophenyl)-N …

Little evidence has been available on the oxidative pathways of glutamine and glutamate,
the major respiratory substrates of cancer cells. Glutamate formed from glutamine by …

Thioredoxin 2 (Trx-2) is a small redox protein containing the thioredoxin active site Trp-Cys-
Gly-Pro-Cys that is localized to the mitochondria by a mitochondrial leader sequence and …

A tumorigenic anchorage-dependent cell line (H-91) was established in culture from an azo-
dye-induced rat ascites hepatoma. When grown in a glucose-containing medium the cells …

The production of NO⋅ by mitochondria was investigated by electron paramagnetic
resonance using the spin-trapping technique, and by the oxidation of oxymyoglobin. Percoll …

Acetaminophen or paracetamol (APAP) overdose is a common cause of liver injury.
Silymarin (SLM) is a hepatoprotective agent widely used for treating liver injury of different …

Rat liver cytoplasm (postnuclear supernatant) has a low aerobic glycolytic rate in the
presence of added glucose, ATP, ADP, Pi, and NAD+, whereas cytoplasm from Ehrlich …