Recent insights into nanotechnology in colorectal cancer

AAZ Dezfuli, M Abu-Elghait, SS Salem - Applied Biochemistry and …, 2023 - Springer
Colorectal cancer (CRC) is the third cancer among the known causes of cancer that impact
people. Although CRC drug options are imperfect, primary detection of CRC can play a key …

Genetically engineered pigs as models for human disease

C Perleberg, A Kind… - Disease models & …, 2018 - journals.biologists.com
Genetically modified animals are vital for gaining a proper understanding of disease
mechanisms. Mice have long been the mainstay of basic research into a wide variety of …

Colorectal cancer: epidemiology, disease mechanisms and interventions to reduce onset and mortality

V Aran, AP Victorino, LC Thuler, CG Ferreira - Clinical colorectal cancer, 2016 - Elsevier
Colorectal cancer (CRC) is a multifactorial disease resulting from lifestyle, genetic, and
environmental factors. There are hereditary and non-hereditary CRC types; however, the …

[HTML][HTML] Serrated pathway in colorectal carcinogenesis

L Yamane, C Scapulatempo-Neto… - World journal of …, 2014 - ncbi.nlm.nih.gov
Serrated adenocarcinoma is a recently described subset of colorectal cancer (CRC), which
account for about 10% of all CRCs and follows an alternative pathway in which serrated …

Mathematical modelling of molecular pathways enabling tumour cell invasion and migration

DPA Cohen, L Martignetti, S Robine… - PLoS computational …, 2015 - journals.plos.org
Understanding the etiology of metastasis is very important in clinical perspective, since it is
estimated that metastasis accounts for 90% of cancer patient mortality. Metastasis results …

[HTML][HTML] Mutant KRAS as a critical determinant of the therapeutic response of colorectal cancer

K Knickelbein, L Zhang - Genes & diseases, 2015 - Elsevier
Mutations in the KRAS oncogene represent one of the most prevalent genetic alterations in
colorectal cancer (CRC), the third leading cause of cancer-related death in the US. In …

Colorectal cancer: from genetic landscape to targeted therapy

M El Bali, J Bakkach, M Bennani Mechita - Journal of Oncology, 2021 - Wiley Online Library
Colorectal cancer (CRC) is the third most common cancer type and the second cause of
death worldwide. The advancement in understanding molecular pathways involved in CRC …

[HTML][HTML] Targeting mTOR network in colorectal cancer therapy

XW Wang, YJ Zhang - World journal of gastroenterology: WJG, 2014 - ncbi.nlm.nih.gov
The mechanistic target of rapamycin (mTOR) integrates growth factor signals with cellular
nutrient and energy levels and coordinates cell growth, proliferation and survival. A …

Revisiting the therapeutic potential of gingerols against different pharmacological activities

S Sharma, MK Shukla, KC Sharma, Tirath… - Naunyn-Schmiedeberg's …, 2023 - Springer
The rhizomes of ginger have been in use in many forms of traditional and alternative
medicines. Besides being employed as condiment and flavoring agent, it is used in the …

Gingerol and its role in chronic diseases

YA Mohd Yusof - Drug discovery from mother nature, 2016 - Springer
Since antiquity, ginger or Zingiber officinale, has been used by humans for medicinal
purposes and as spice condiments to enhance flavor in cooking. Ginger contains many …