Chirality of pharmaceutical substances is an important aspect in drug research because it
determines how enantiomers will interact with chiral biological targets. Enantiomers of a …

The human arterial system in youth is beautifully designed for its role of receiving spurts of
blood from the left ventricle and distributing this as steady flow through peripheral …

In recent years, great emphasis has been placed on the role of arterial stiffness in the
development of cardiovascular diseases. Indeed, the assessment of arterial stiffness is …

The goal of this study was to review the origin, clinical relevance and treatment of pulse
pressure (PP). Elevated PP is increasingly being recognized as a risk factor for …

In vivo arterial stiffness is a dynamic property based on vascular function and structure. It is
influenced by confounding factors like blood pressure (BP), age, gender, body mass index …

Background There is increasing evidence of a link between conduit vessel stiffness and
cardiovascular events, although the association has never been tested in a large post …

Background Cardiovascular diseases are the most common cause of disability and death
among subjects with non–insulin-dependent diabetes mellitus (NIDDM). The atherosclerotic …

Our objective was to validate a carotid artery tonometry–derived augmentation index as a
means to estimate augmentation index (AI) of ascending aortic pressure under various …

Cardiac and arterial interactions in end-stage renal disease. Although cardiac hypertrophy is
a frequent complication of end-stage renal disease (ESRD), relatively little is known about …

The β-blocker atenolol is less effective than angiotensin-receptor blockers and calcium-
channel blockers for reducing central blood pressure (BP). The trial was designed to …