Comparative genomics reveals high biological diversity and specific adaptations in the industrially and medically important fungal genus Aspergillus
Abstract Background The fungal genus Aspergillus is of critical importance to humankind.
Species include those with industrial applications, important pathogens of humans, animals …
Species include those with industrial applications, important pathogens of humans, animals …
[HTML][HTML] Endocytosis of nutrient transporters in fungi: The ART of connecting signaling and trafficking
Plasma membrane transporters play pivotal roles in the import of nutrients, including sugars,
amino acids, nucleobases, carboxylic acids, and metal ions, that surround fungal cells. The …
amino acids, nucleobases, carboxylic acids, and metal ions, that surround fungal cells. The …
Dissection of transporter function: from genetics to structure
G Diallinas - Trends in Genetics, 2016 - cell.com
Transporters are transmembrane proteins mediating the selective uptake or efflux of solutes,
metabolites, drugs, or ions across cellular membranes. Despite their immense biological …
metabolites, drugs, or ions across cellular membranes. Despite their immense biological …
Origin, diversification and substrate specificity in the family of NCS 1/FUR transporters
NCS 1 proteins are H+/Na+ symporters specific for the uptake of purines, pyrimidines and
related metabolites. In this article, we study the origin, diversification and substrate specificity …
related metabolites. In this article, we study the origin, diversification and substrate specificity …
Uracil/H+ Symport by FurE Refines Aspects of the Rocking-bundle Mechanism of APC-type Transporters
Transporters mediate the uptake of solutes, metabolites and drugs across the cell
membrane. The eukaryotic FurE nucleobase/H+ symporter of Aspergillus nidulans has been …
membrane. The eukaryotic FurE nucleobase/H+ symporter of Aspergillus nidulans has been …
The arrestin‐like protein ArtA is essential for ubiquitination and endocytosis of the UapA transporter in response to both broad‐range and specific signals
M Karachaliou, S Amillis, M Evangelinos… - Molecular …, 2013 - Wiley Online Library
We investigated the role of all arrestin‐like proteins of A spergillus nidulans in respect to
growth, morphology, sensitivity to drugs and specifically for the endocytosis and turnover of …
growth, morphology, sensitivity to drugs and specifically for the endocytosis and turnover of …
Transport assays in filamentous fungi: kinetic characterization of the UapC purine transporter of Aspergillus nidulans
E Krypotou, G Diallinas - Fungal Genetics and Biology, 2014 - Elsevier
Transport assays allow the direct kinetic analysis of a specific transporter by measuring
apparent K m and V max values, and permit the characterization of substrate specificity …
apparent K m and V max values, and permit the characterization of substrate specificity …
Modeling, substrate docking, and mutational analysis identify residues essential for the function and specificity of a eukaryotic purine-cytosine NCS1 transporter
E Krypotou, V Kosti, S Amillis… - Journal of Biological …, 2012 - ASBMB
The recent elucidation of crystal structures of a bacterial member of the NCS1 family, the
Mhp1 benzyl-hydantoin permease from Microbacterium liquefaciens, allowed us to construct …
Mhp1 benzyl-hydantoin permease from Microbacterium liquefaciens, allowed us to construct …
Allantoin transport protein, PucI, from Bacillus subtilis: evolutionary relationships, amplified expression, activity and specificity
This work reports the evolutionary relationships, amplified expression, functional
characterization and purification of the putative allantoin transport protein, PucI, from …
characterization and purification of the putative allantoin transport protein, PucI, from …
Genome-wide detection of genes under positive selection in worldwide populations of the barley scald pathogen
N Mohd-Assaad, BA McDonald… - Genome biology and …, 2018 - academic.oup.com
Coevolution between hosts and pathogens generates strong selection pressures to maintain
resistance and infectivity, respectively. Genomes of plant pathogens often encode major …
resistance and infectivity, respectively. Genomes of plant pathogens often encode major …