From gut microbiota to host appetite: gut microbiota-derived metabolites as key regulators
H Han, B Yi, R Zhong, M Wang, S Zhang, J Ma, Y Yin… - Microbiome, 2021 - Springer
Feelings of hunger and satiety are the key determinants for maintaining the life of humans
and animals. Disturbed appetite control may disrupt the metabolic health of the host and …
and animals. Disturbed appetite control may disrupt the metabolic health of the host and …
[HTML][HTML] Functions of gut microbiota metabolites, current status and future perspectives
J Liu, Y Tan, H Cheng, D Zhang, W Feng… - Aging and …, 2022 - ncbi.nlm.nih.gov
Gut microbiota, a collection of microorganisms that live within gastrointestinal tract, provides
crucial signaling metabolites for the physiological of hosts. In healthy state, gut microbiota …
crucial signaling metabolites for the physiological of hosts. In healthy state, gut microbiota …
[HTML][HTML] In Alzheimer's disease, 6-month treatment with GLP-1 analog prevents decline of brain glucose metabolism: randomized, placebo-controlled, double-blind …
In animal models, the incretin hormone GLP-1 affects Alzheimer's disease (AD). We
hypothesized that treatment with GLP-1 or an analogue of GLP-1 would prevent …
hypothesized that treatment with GLP-1 or an analogue of GLP-1 would prevent …
GLP-1 receptor activation modulates appetite-and reward-related brain areas in humans
L van Bloemendaal, RG IJzerman, JS Ten Kulve… - Diabetes, 2014 - Am Diabetes Assoc
Gut-derived hormones, such as GLP-1, have been proposed to relay information to the brain
to regulate appetite. GLP-1 receptor agonists, currently used for the treatment of type 2 …
to regulate appetite. GLP-1 receptor agonists, currently used for the treatment of type 2 …
GLP-1 receptor signaling in astrocytes regulates fatty acid oxidation, mitochondrial integrity, and function
K Timper, A del Río-Martín, AL Cremer, S Bremser… - Cell metabolism, 2020 - cell.com
Astrocytes represent central regulators of brain glucose metabolism and neuronal function.
They have recently been shown to adapt their function in response to alterations in …
They have recently been shown to adapt their function in response to alterations in …
Glucagon-like peptide-1 and the central/peripheral nervous system: crosstalk in diabetes
G Muscogiuri, RA DeFronzo, A Gastaldelli… - Trends in Endocrinology …, 2017 - cell.com
Glucagon-like peptide-1 (GLP-1) is released in response to meals and exerts important roles
in the maintenance of normal glucose homeostasis. GLP-1 is also important in the regulation …
in the maintenance of normal glucose homeostasis. GLP-1 is also important in the regulation …
Physiology of incretins (GIP and GLP-1) and abnormalities in type 2 diabetes
JF Gautier, SP Choukem, J Girard - Diabetes & metabolism, 2008 - Elsevier
Incretin hormones are defined as intestinal hormones released in response to nutrient
ingestion, which potentiate the glucose-induced insulin response. In humans, the incretin …
ingestion, which potentiate the glucose-induced insulin response. In humans, the incretin …
Glucagon-like peptide-1 (GLP-1) and the regulation of human invariant natural killer T cells: lessons from obesity, diabetes and psoriasis
Aims/hypothesis The innate immune cells, invariant natural killer T cells (iNKT cells), are
implicated in the pathogenesis of psoriasis, an inflammatory condition associated with …
implicated in the pathogenesis of psoriasis, an inflammatory condition associated with …
Brain reward‐system activation in response to anticipation and consumption of palatable food is altered by glucagon‐like peptide‐1 receptor activation in humans
L van Bloemendaal, DJ Veltman… - Diabetes, Obesity …, 2015 - Wiley Online Library
Aim To test the hypothesis that food intake reduction after glucagon‐like peptide‐1 (GLP‐1)
receptor activation is mediated through brain areas regulating anticipatory and …
receptor activation is mediated through brain areas regulating anticipatory and …
Pathophysiology linking depression and type 2 diabetes: psychotherapy, physical exercise, and fecal microbiome transplantation as damage control
Diabetes increases the likelihood of developing depression and vice versa. Research on
this bidirectional association has somewhat managed to delineate the interplay among …
this bidirectional association has somewhat managed to delineate the interplay among …