[HTML][HTML] Versatile applications of cyanobacteria in biotechnology

E Żymańczyk-Duda, SO Samson, M Brzezińska-Rodak… - Microorganisms, 2022 - mdpi.com
Cyanobacteria are blue-green Gram-negative and photosynthetic bacteria which are seen
as one of the most morphologically numerous groups of prokaryotes. Because of their ability …

[HTML][HTML] Bioactive substances of cyanobacteria and microalgae: sources, metabolism, and anticancer mechanism insights

A Bouyahya, S Bakrim, I Chamkhi, D Taha… - Biomedicine & …, 2024 - Elsevier
Cyanobacteria and microalgae contain various phytochemicals, including bioactive
components in the form of secondary metabolites, namely flavonoids, phenolic acids …

A comprehensive review of the therapeutic potential of cyanobacterial marine bioactives: Unveiling the hidden treasures of the sea

T Nawaz, L Gu, S Fahad, S Saud, Z Jiang… - Food and Energy …, 2023 - Wiley Online Library
Marine cyanobacterial bioactives, due to their diverse chemistry and promising
pharmacological properties, hold significant potential as therapeutic agents. Here, we …

Methods in marine natural product drug discovery: what's new?

J Almaliti, WH Gerwick - Expert Opinion on Drug Discovery, 2023 - Taylor & Francis
Natural products (NPs) remain as a leading source of new inspirational scaffolds and
pharmacophores for the development of pharmaceuticals. Marine organisms, while still …

[HTML][HTML] Study of marine microorganism metabolites: New resources for bioactive natural products

N Barzkar, S Sukhikh, O Babich - Frontiers in Microbiology, 2024 - frontiersin.org
The marine environment has remained a source of novel biological molecules with
diversified applications. The ecological and biological diversity, along with a unique physical …

New phenothiazine conjugates as apoptosis inducing agents: Design, synthesis, In-vitro anti-cancer screening and 131I-radiolabeling for in-vivo evaluation

MO Sarhan, H Haffez, NA Elsayed, RS El-Haggar… - Bioorganic …, 2023 - Elsevier
Phenothiazines (PTZs) are a group of compounds characterized by the presence of the 10H-
dibenzo-[b, e]-1, 4-thiazine system. PTZs used in clinics as antipsychotic drugs with other …

[HTML][HTML] Enhancement of Anticancer, Antibacterial, and Acetylcholinesterase Inhibition Activities from Oscillatoria sancta under Starvation Conditions

HE Touliabah, DA Refaay - Water, 2023 - mdpi.com
The growth response and biological activity of the cyanobacterium Oscillatoria sancta were
investigated in starvation conditions. Oscillatoria sancta growth potential was examined on …

[HTML][HTML] Recent Advancement in Anticancer Compounds from Marine Organisms: Approval, Use and Bioinformatic Approaches to Predict New Targets

G Santaniello, A Nebbioso, L Altucci, M Conte - Marine Drugs, 2022 - mdpi.com
In recent years, the study of anticancer bioactive compounds from marine sources has
received wide interest. Contextually, world regulatory authorities have approved several …

[HTML][HTML] Marine cyanobacterial peptides in neuroblastoma: Search for better therapeutic options

S Ahmed, W Alam, M Aschner, R Filosa, WS Cheang… - Cancers, 2023 - mdpi.com
Simple Summary This review describes the anticancer activities of several marine peptides
isolated from cyanobacteria and their specific effects against neuroblastoma. After a short …

An update on the development on tubulin inhibitors for the treatment of solid tumors

PA Yakkala, S Rahaman, PSL Soukya… - Expert Opinion on …, 2024 - Taylor & Francis
Introduction Microtubules play a vital role in cancer therapeutics. They are implicated in
tumorigenesis, thus inhibiting tubulin polymerization in cancer cells, and have now become …