Cancer is a class of diseases characterized by uncontrolled cell growth and has the ability to
spread or metastasize throughout the body. In recent years, remarkable progress has been …

The human response to ionizing radiation (IR) varies among individuals. The first evidence
of the individual response to IR was reported in the beginning of the 20th century …

Background DNA repair pathways, cell cycle arrest checkpoints, and cell death induction are
present in cells to process DNA damage and prevent genomic instability caused by various …

Radiotherapy is a powerful cure for several types of solid tumours, but its application is often
limited because of severe side effects in individual patients. With the aim to find biomarkers …

Cancer risk and radiation sensitivity are often associated with alterations in DNA repair, cell
cycle, or apoptotic pathways. Interindividual variability in mutagen or radiation sensitivity and …

Physical activity offers a paradoxical hormetic effect and a health benefit to cancer survivors;
however, the biochemical mechanisms have not been entirely elucidated. Despite the well …

Therapeutic exposure to ionising radiation can induce normal tissue side effects which
consistently differ among individuals suggesting a possible genetic control. One approach to …

To meet the anabolic demands of the proliferative potential of tumor cells, malignant cells
tend to rewire their metabolic pathways. Although different types of malignant cells share this …

To compare the extent of sperm DNA damage with the degree of protamine deficiency in
spermatozoa of normal and subfertile individuals, 30 semen samples from three groups of …

Although radiation carcinogenesis has been shown both experimentally and
epidemiologically, the use of ionizing radiation is also one of the major modalities in cancer …