Widespread gene-environment interactions shape the immune response to SARS-CoV-2 infection in hospitalized COVID-19 patients
HE Randolph, R Aguirre-Gamboa… - bioRxiv, 2024 - biorxiv.org
Genome-wide association studies performed in patients with coronavirus disease 2019
(COVID-19) have uncovered various loci significantly associated with susceptibility to SARS …
(COVID-19) have uncovered various loci significantly associated with susceptibility to SARS …
Context-specific eQTLs reveal causal genes underlying shared genetic architecture of critically ill COVID-19 and idiopathic pulmonary fibrosis
Most genetic variants identified through genome-wide association studies (GWAS) are
suspected to be regulatory in nature, but only a small fraction colocalize with expression …
suspected to be regulatory in nature, but only a small fraction colocalize with expression …
Identifying Potential Drug Targets for the Treatment of Ulcerative Colitis Using Mendelian Randomization Combined with Co-localization Analysis
T Zhang - 2024 - researchsquare.com
Purpose To identify potential therapeutic targets for ulcerative colitis by integrating
Mendelian randomization (MR) and Bayesian colocalization analysis to pinpoint gene …
Mendelian randomization (MR) and Bayesian colocalization analysis to pinpoint gene …