The immunological balance between host and parasite in malaria
K Deroost, TT Pham, G Opdenakker… - FEMS microbiology …, 2016 - academic.oup.com
Coevolution of humans and malaria parasites has generated an intricate balance between
the immune system of the host and virulence factors of the parasite, equilibrating maximal …
the immune system of the host and virulence factors of the parasite, equilibrating maximal …
Pathogenetic mechanisms and treatment targets in cerebral malaria
Malaria, the most prevalent mosquito-borne infectious disease worldwide, has accompanied
humanity for millennia and remains an important public health issue despite advances in its …
humanity for millennia and remains an important public health issue despite advances in its …
Lipid hijacking: a unifying theme in vector-borne diseases
Vector-borne illnesses comprise a significant portion of human maladies, representing 17%
of global infections. Transmission of vector-borne pathogens to mammals primarily occurs …
of global infections. Transmission of vector-borne pathogens to mammals primarily occurs …
The malaria parasite has an intrinsic clock
Malarial rhythmic fevers are the consequence of the synchronous bursting of red blood cells
(RBCs) on completion of the malaria parasite asexual cell cycle. Here, we hypothesized that …
(RBCs) on completion of the malaria parasite asexual cell cycle. Here, we hypothesized that …
Cerebral malaria: current clinical and immunological aspects
K Albrecht-Schgoer, P Lackner… - Frontiers in …, 2022 - frontiersin.org
This review focuses on current clinical and immunological aspects of cerebral malaria
induced by Plasmodium falciparum infection. Albeit many issues concerning the …
induced by Plasmodium falciparum infection. Albeit many issues concerning the …
Tissue tropism in parasitic diseases
S Silva Pereira, S Trindade, M De Niz… - Open …, 2019 - royalsocietypublishing.org
Parasitic diseases, such as sleeping sickness, Chagas disease and malaria, remain a major
cause of morbidity and mortality worldwide, but particularly in tropical, developing countries …
cause of morbidity and mortality worldwide, but particularly in tropical, developing countries …
Tissue-specific immunopathology during malaria infection
Systemic inflammation mediated by Plasmodium parasites is central to malaria disease and
its complications. Plasmodium parasites reside in erythrocytes and can theoretically reach …
its complications. Plasmodium parasites reside in erythrocytes and can theoretically reach …
Pathogenesis of malaria-associated acute respiratory distress syndrome
PE Van den Steen, K Deroost, J Deckers… - Trends in …, 2013 - cell.com
Malaria-associated acute respiratory distress syndrome (MA-ARDS) is an increasingly
reported, often lethal, and incompletely understood complication of malaria. We discuss and …
reported, often lethal, and incompletely understood complication of malaria. We discuss and …
[HTML][HTML] Comparative spatial proteomics of Plasmodium-infected erythrocytes
Plasmodium parasites contribute to one of the highest global infectious disease burdens. To
achieve this success, the parasite has evolved a range of specialized subcellular …
achieve this success, the parasite has evolved a range of specialized subcellular …
The Plasmodium translocon of exported proteins (PTEX) component thioredoxin‐2 is important for maintaining normal blood‐stage growth
K Matthews, M Kalanon, SA Chisholm… - Molecular …, 2013 - Wiley Online Library
P lasmodium parasites remodel their vertebrate host cells by translocating hundreds of
proteins across an encasing membrane into the host cell cytosol via a putative export …
proteins across an encasing membrane into the host cell cytosol via a putative export …