[HTML][HTML] Helminth immunoregulation: the role of parasite secreted proteins in modulating host immunity
Helminths are masterful immunoregulators. A characteristic feature of helminth infection is a
Th2-dominated immune response, but stimulation of immunoregulatory cell populations …
Th2-dominated immune response, but stimulation of immunoregulatory cell populations …
Helminth allergens, parasite-specific IgE, and its protective role in human immunity
CM Fitzsimmons, FH Falcone, DW Dunne - Frontiers in immunology, 2014 - frontiersin.org
The Th2 immune response, culminating in eosinophilia and IgE production, is not only
characteristic of allergy but also of infection by parasitic worms (helminths). Anti-parasite IgE …
characteristic of allergy but also of infection by parasitic worms (helminths). Anti-parasite IgE …
[HTML][HTML] Particularities of allergy in the Tropics
Allergic diseases are distributed worldwide and their risk factors and triggers vary according
to geographical and socioeconomic conditions. Allergies are frequent in the Tropics but …
to geographical and socioeconomic conditions. Allergies are frequent in the Tropics but …
Immune modulation and modulators in Heligmosomoides polygyrus infection
RM Maizels, JP Hewitson, J Murray, YM Harcus… - Experimental …, 2012 - Elsevier
The intestinal nematode parasite Heligmosomoides polygyrus bakeri exerts widespread
immunomodulatory effects on both the innate and adaptive immune system of the host …
immunomodulatory effects on both the innate and adaptive immune system of the host …
The secreted and surface proteomes of the adult stage of the carcinogenic human liver fluke Opisthorchis viverrini
Infection with the human liver fluke, Opisthorchis viverrini, is a serious public health problem
in Thailand, Laos and nearby locations in Southeast Asia. Both experimental and …
in Thailand, Laos and nearby locations in Southeast Asia. Both experimental and …
A portrait of the “SCP/TAPS” proteins of eukaryotes—developing a framework for fundamental research and biotechnological outcomes
C Cantacessi, BE Campbell, A Visser, P Geldhof… - Biotechnology …, 2009 - Elsevier
A wide range of proteins belonging to the SCP/TAPS “family” has been described for various
eukaryotic organisms, including plants and animals (vertebrates and invertebrates, such as …
eukaryotic organisms, including plants and animals (vertebrates and invertebrates, such as …
Anti-schistosomal intervention targets identified by lifecycle transcriptomic analyses
JM Fitzpatrick, E Peak, S Perally… - PLoS neglected …, 2009 - journals.plos.org
Background Novel methods to identify anthelmintic drug and vaccine targets are urgently
needed, especially for those parasite species currently being controlled by singular, often …
needed, especially for those parasite species currently being controlled by singular, often …
Cytosine methylation regulates oviposition in the pathogenic blood fluke Schistosoma mansoni
Similar to other metazoan pathogens, Schistosoma mansoni undergoes transcriptional and
developmental regulation during its complex lifecycle and host interactions. DNA …
developmental regulation during its complex lifecycle and host interactions. DNA …
What helminth genomes have taught us about parasite evolution
M Zarowiecki, M Berriman - Parasitology, 2015 - cambridge.org
The genomes of more than 20 helminths have now been sequenced. Here we perform a
meta-analysis of all sequenced genomes of nematodes and Platyhelminthes, and attempt to …
meta-analysis of all sequenced genomes of nematodes and Platyhelminthes, and attempt to …
Gene Expression Patterns in Larval Schistosoma mansoni Associated with Infection of the Mammalian Host
SJ Parker-Manuel, AC Ivens, GP Dillon… - PLoS neglected …, 2011 - journals.plos.org
Background The infective schistosome cercaria develops within the intramolluscan daughter
sporocyst from an undifferentiated germ ball, during which synthesis of proteins essential for …
sporocyst from an undifferentiated germ ball, during which synthesis of proteins essential for …