Biliary atresia

JL Hartley, M Davenport, DA Kelly - The Lancet, 2009 - thelancet.com
Biliary atresia is a rare disease of infancy, which has changed within 30 years from being
fatal to being a disorder for which effective palliative surgery or curative liver transplantation …

The pathogenesis of biliary atresia: evidence for a virus-induced autoimmune disease

CL Mack - Seminars in liver disease, 2007 - thieme-connect.com
Biliary atresia is a mystifying cause of neonatal cholestasis, manifested by progressive
inflammation and fibrosis of both the extrahepatic and intrahepatic bile ducts. It is a …

Use of corticosteroids after hepatoportoenterostomy for bile drainage in infants with biliary atresia: the START randomized clinical trial

JA Bezerra, C Spino, JC Magee, BL Shneider… - Jama, 2014 - jamanetwork.com
Importance Biliary atresia is the most common cause of end-stage liver disease in children.
Controversy exists as to whether use of steroids after hepatoportoenterostomy improves …

Current management of biliary atresia

DA Kelly, M Davenport - Archives of disease in childhood, 2007 - adc.bmj.com
Extra-hepatic biliary atresia occurs in approximately 1: 15 000 live births leading to about 50
new cases/year in the UK. Presentation is with prolonged jaundice, usually in a term baby …

Biliary atresia: 50 years after the first Kasai

BE Wildhaber - International Scholarly Research Notices, 2012 - Wiley Online Library
Biliary atresia is a rare neonatal disease of unknown etiology, where obstruction of the
biliary tree causes severe cholestasis, leading to biliary cirrhosis and death in the first years …

[PDF][PDF] Randomized, double‐blind, placebo‐controlled trial of corticosteroids after Kasai portoenterostomy for biliary atresia

M Davenport, MD Stringer, SA Tizzard, P McClean… - …, 2007 - Wiley Online Library
The objective of this study was to evaluate adjuvant corticosteroids after Kasai
portoenterostomy for biliary atresia. The study consisted of a prospective, 2‐center, double …

Steroids in biliary atresia: single surgeon, single centre, prospective study

M Davenport, C Parsons, S Tizzard, N Hadzic - Journal of hepatology, 2013 - Elsevier
Background & Aims The effect of adjuvant steroids in infants with biliary atresia (BA) is not
clear and evidence of benefit is lacking. Methods During the period Jan. 2000–Dec. 2011 …

Steroids after the Kasai procedure for biliary atresia: the effect of age at Kasai portoenterostomy

A Tyraskis, M Davenport - Pediatric surgery international, 2016 - Springer
The use of adjuvant steroids following Kasai porteoenterostomy (KPE) for biliary atresia is
controversial. The aim of this study was twofold: a systematic review of published literature …

Biliary atresia

G Mieli-Vergani, D Vergani - Seminars in immunopathology, 2009 - Springer
Biliary atresia (BA) is a condition unique to infancy. It results from inflammatory destruction of
the intrahepatic and extrahepatic bile ducts. It is the most frequent surgically correctable liver …

Postoperative steroid therapy for biliary atresia: systematic review and meta-analysis

Y Chen, SA Nah, L Chiang, G Krishnaswamy… - Journal of pediatric …, 2015 - Elsevier
Abstract Background/Objectives Adjuvant steroid therapy has become popular in the
postoperative management of biliary atresia. However, the benefits of steroid therapy are …