Mutational inactivation of the DICER1 gene causes aberrant micro-RNA maturation, which in
turn may have consequences for the posttranscriptional regulation of gene expression …

The noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) is a
strictly defined thyroid lesion, reclassified in 2016, in order to more accurately reflect the …

Follicular-patterned tumors of the thyroid in the adult population frequently harbor RAS
mutations or PAX8-PPARG rearrangement, but little is known about molecular profiles in the …

Thyroid gland teratomas are rare tumors that span a wide clinicopathologic spectrum.
Although benign and immature teratomas arise in infants and young children and generally …

It is a well-known and intensively studied phenomenon that the levels of many miRNAs are
differentiated in cancer. miRNA biogenesis and functional expression are complex …

Background Mutations in micro-RNA (miRNA) regulators DICER1 and DGCR8 have recently
been uncovered, revealing a potential novel mechanism driving thyroid tumor development …

Background Papillary thyroid carcinoma (PTC) is the most common type of thyroid cancer
(TC). Several genomic and transcriptomic studies explored the molecular landscape of …

DGCR8 emerged recently as miRNAs biogenesis pathway protein with a highlighted role in
thyroid disease. This study aimed to characterize this miRNA biogenesis component, in …

Enterovirus (EV) infection of insulin-producing pancreatic beta cells is associated with type 1
diabetes (T1D), but little is known about the mechanisms that lead the virus to cause a …

Thyroid cancer is the most frequent endocrine malignancy with the majority of cases derived
from thyroid follicular cells and caused by sporadic mutations. However, when at least two or …