Static and dynamic: evolving biomaterial mechanical properties to control cellular mechanotransduction
The extracellular matrix (ECM) is a highly dynamic system that constantly offers physical,
biological, and chemical signals to embraced cells. Increasing evidence suggests that …
biological, and chemical signals to embraced cells. Increasing evidence suggests that …
Regulation of stem cell fate using nanostructure-mediated physical signals
Y Kong, J Duan, F Liu, L Han, G Li, C Sun… - Chemical Society …, 2021 - pubs.rsc.org
One of the major issues in tissue engineering is regulation of stem cell differentiation toward
specific lineages. Unlike biological and chemical signals, physical signals with adjustable …
specific lineages. Unlike biological and chemical signals, physical signals with adjustable …
Bioinspired mild photothermal effect-reinforced multifunctional fiber scaffolds promote bone regeneration
Bone fractures are often companied with poor bone healing and high rates of infection. Early
recruitment of mesenchymal stem cells (MSCs) is critical for initiating efficient bone repair …
recruitment of mesenchymal stem cells (MSCs) is critical for initiating efficient bone repair …
Highly Effective and Noninvasive Near‐Infrared Eradication of a Staphylococcus aureus Biofilm on Implants by a Photoresponsive Coating within 20 Min
M Li, L Li, K Su, X Liu, T Zhang, Y Liang… - Advanced …, 2019 - Wiley Online Library
Biofilms have been related to the persistence of infections on medical implants, and these
cannot be eradicated because of the resistance of biofilm structures. Therefore, a …
cannot be eradicated because of the resistance of biofilm structures. Therefore, a …
Programmable integrin and N-cadherin adhesive interactions modulate mechanosensing of mesenchymal stem cells by cofilin phosphorylation
Z Zhang, B Sha, L Zhao, H Zhang, J Feng… - Nature …, 2022 - nature.com
During mesenchymal development, the sources of mechanical forces transduced by cells
transition over time from predominantly cell-cell interactions to predominantly cell …
transition over time from predominantly cell-cell interactions to predominantly cell …
Biomimetic micro/nano structures for biomedical applications
Cell behaviors are influenced by the surrounding dynamic microenvironment where the
extracellular matrix (ECM) composed of different micro/nano-structures plays a key role …
extracellular matrix (ECM) composed of different micro/nano-structures plays a key role …
Manipulating cell fate: dynamic control of cell behaviors on functional platforms
W Li, Z Yan, J Ren, X Qu - Chemical Society Reviews, 2018 - pubs.rsc.org
The cell microenvironment choreographs the behaviors of cells through multiple well-
controlled signals. For basic biological study and cell-based therapies, it is essential to …
controlled signals. For basic biological study and cell-based therapies, it is essential to …
Manipulating nanoparticle aggregates regulates receptor–ligand binding in macrophages
Y Kim, HJ Jung, Y Lee, S Koo, R Thangam… - Journal of the …, 2022 - ACS Publications
The receptor–ligand interactions in cells are dynamically regulated by modulation of the
ligand accessibility. In this study, we utilize size-tunable magnetic nanoparticle aggregates …
ligand accessibility. In this study, we utilize size-tunable magnetic nanoparticle aggregates …
Modulation of macrophages by in situ ligand bridging
Extracellular matrix (ECM) proteins containing cell‐attachable Arg‐Gly‐Asp (RGD)
sequences exhibit variable bridging and non‐bridging in fibronectin‐collagen and laminin …
sequences exhibit variable bridging and non‐bridging in fibronectin‐collagen and laminin …
Arrowhead composite microneedle patches with anisotropic surface adhesion for preventing intrauterine adhesions
Biomedical patches are considered as a promising strategy to help tissue repair and
regeneration, prevent tissue adhesion, and reduce neighboring friction. Here, novel …
regeneration, prevent tissue adhesion, and reduce neighboring friction. Here, novel …