Myelin is critical for the proper function of the nervous system and one of the most complex
cell–cell interactions of the body. Myelination allows for the rapid conduction of action …

The brain is highly enriched with fatty acids. These include the polyunsaturated fatty acids
(PUFAs) arachidonic acid and docosahexaenoic acid, which are largely esterified to the …

In the brain, mitochondrial metabolism has been largely associated with energy production,
and its dysfunction is linked to neuronal cell loss. However, the functional role of …

It is puzzling that hydrogen-rich fatty acids are used only poorly as fuel in the brain. The long-
standing belief that a slow passage of fatty acids across the blood–brain barrier might be the …

Lipids in the brain are major components playing structural functions as well as
physiological roles in nerve cells, such as neural communication, neurogenesis, synaptic …

Docosahexaenoic acid (DHA) is important for brain function, and can be obtained directly
from the diet or synthesized in the body from α-linolenic acid (ALA). Debate exists as to …

The retinal pigment epithelium-photoreceptor interphase is renewed each day in a stunning
display of cellular interdependence. While photoreceptors use photosensitive pigments to …

Many prospective studies have shown that a diet enriched in omega-3 polyunsaturated fatty
acids (n-3 PUFAs) can improve cognitive function during normal aging and prevent the …

Essential polyunsaturated fatty acids (PUFAs) have profound effects on brain development
and function. Abnormalities of PUFA status have been implicated in neuropsychiatric …

Docosahexaenoic acid (DHA) is the most abundant n-3 polyunsaturated fatty acid in the
brain where it serves to regulate several important processes and, in addition, serves as a …