Coiled‐coils are found in proteins throughout all three kingdoms of life. Coiled‐coil domains
of some proteins are almost invariant in sequence and length, betraying a structural and …

Members of the Rab or ARF/Sar branches of the Ras GTPase superfamily regulate almost
every step of intracellular membrane traffic. A rapidly growing body of evidence indicates …

Golgi apparatus (GA) oxidative stress induced by in situ reactive oxygen species (ROS)
could severely damage the morphology and function of GA, which may open up an avenue …

A number of long coiled-coil proteins are present on the Golgi. Often referred to as “golgins,”
they are well conserved in evolution and at least five are likely to have been present in the …

Golgins are a family of coiled-coil proteins associated with the Golgi apparatus necessary for
tethering events in membrane fusion and as structural supports for Golgi cisternae. Recent …

Protein transport between organelles is mediated by vesicles which must accurately dock
and fuse with appropriate compartments. Over the past several years a large number of long …

Membrane traffic between the endoplasmic reticulum (ER) and Golgi apparatus and through
the Golgi apparatus is a highly regulated process controlled by members of the rab GTPase …

p115 tethers coat protein (COP) I vesicles to Golgi membranes. The acidic COOH-terminal
domain of p115 links the Golgins, Giantin on COPI vesicles, to GM130 on Golgi membranes …

Protein egress from the endoplasmic reticulum (ER) is driven by a conserved cytoplasmic
coat complex called the COPII coat. The COPII coat complex contains an inner shell …

Coiled-coil and multisubunit tethers have emerged as key regulators of membrane traffic
and organellar architecture. The restricted subcellular localization of tethers and their ability …