Pneumonia and its sequelae, acute lung injury, present unique challenges for pulmonary
and critical care healthcare professionals, and these challenges have recently garnered …

Acute respiratory distress syndrome (ARDS) is an acute and diffuse inflammatory lung injury
in a short time, one of the common severe manifestations of the respiratory system that …

Macrophages undergoing M1-versus M2-type polarization differ significantly in their cell
metabolism and cellular functions. Here, global quantitative time-course proteomics and …

Acute kidney injury (AKI) is defined by a rapid decline in renal function. Regardless of the
initial cause of injury, the influx of immune cells is a common theme during AKI. While an …

Atherosclerosis, a disease process characterized by lipid accumulation and inflammation, is
the main cause of coronary heart disease (CHD) and myocardial infarction (MI) …

Background Macrophage plasticity allows cells to adopt different phenotypes, a property
with important implications in disorders such as cystic fibrosis (CF) and asthma. Objective …

Rationale: Serial measurements of alveolar macrophage (AM) transcriptional changes in
patients with acute respiratory distress syndrome (ARDS) could identify cell-specific …

Background The multidimensional biological mechanisms underpinning acute respiratory
distress syndrome (ARDS) continue to be elucidated, and early biomarkers for predicting …

Endotoxin tolerance refers to a state refractory to subsequent lipopolysaccharide (LPS)
stimulations following a primary LPS exposure. To study the relationship between endotoxin …

Macrophages modulate the wound healing cascade by adopting different phenotypes such
as pro‐inflammatory (M1) or pro‐wound healing (M2). To reduce M1 activation, the …