Global epidemiology, genetic environment, risk factors and therapeutic prospects of mcr genes: A current and emerging update

M Mmatli, NM Mbelle, J Osei Sekyere - Frontiers in Cellular and …, 2022 - frontiersin.org
Background Mobile colistin resistance (mcr) genes modify Lipid A molecules of the
lipopolysaccharide, changing the overall charge of the outer membrane. Results and …

Mobile Colistin Resistance (mcr) Gene-Containing Organisms in Poultry Sector in Low- and Middle-Income Countries: Epidemiology, Characteristics, and One Health …

MU Anyanwu, IF Jaja, COR Okpala, EO Njoga… - Antibiotics, 2023 - mdpi.com
Mobile colistin resistance (mcr) genes (mcr-1 to mcr-10) are plasmid-encoded genes that
threaten the clinical utility of colistin (COL), one of the highest-priority critically important …

Rapid detection of multiple resistance genes to last-resort antibiotics in Enterobacteriaceae pathogens by recombinase polymerase amplification combined with …

C Lu, J Wang, L Pan, X Gu, W Lu, D Chen… - Frontiers in …, 2023 - frontiersin.org
The worrying emergence of multiple resistance genes to last-resort antibiotics in food
animals and human populations throughout the food chain and relevant environments has …

Epidemiology and Traits of Mobile Colistin Resistance (mcr) Gene-Bearing Organisms from Horses

MU Anyanwu, IF Jaja, OC Nwobi, AC Mgbeahuruike… - Microorganisms, 2022 - mdpi.com
Mobile colistin resistance (mcr) genes (mcr-1 to mcr-10) threaten the efficacy of colistin
(COL), a polymyxin antibiotic that is used as a last-line agent for the treatment of deadly …

[HTML][HTML] Commercial Day-Old Chicks in Nigeria Are Potential Reservoirs of Colistin- and Tigecycline-Resistant Potentially Pathogenic Escherichia coli

MU Anyanwu, NH Ikenna-Ezeh, SC Okafor… - Antibiotics, 2024 - mdpi.com
Background: Frequent use of colistin (COL) and tetracyclines in the Nigerian poultry sector
potentially triggers bacterial resistance against COL and tigecycline (TIG), which are last-line …