Evidence of disturbed insulin signaling in animal models of Alzheimer's disease

SS Alves, G Servilha-Menezes, L Rossi… - Neuroscience & …, 2023 - Elsevier
Since glucose reuptake by neurons is mostly independent of insulin, it has been an
intriguing question whether insulin has or not any roles in the brain. Consequently, the …

Microcapsules based on alginate and guar gum for co-delivery of hydrophobic antitumor bioactives

LM Rebouças, ACC Sousa, CG Sampaio… - Carbohydrate …, 2023 - Elsevier
The main goal was the development of a polysaccharide microcapsule for anticancer
application based on guar gum and sodium alginate for the controlled release of hesperidin …

Curcumin-loaded polymeric nanomaterials as a novel therapeutic strategy for Alzheimer's disease: A comprehensive review

JJ Pei, CP Palanisamy, PM Natarajan… - Ageing Research …, 2024 - Elsevier
Alzheimer's disease (AD) stands as a formidable challenge in modern medicine,
characterized by progressive neurodegeneration, cognitive decline, and memory …

[HTML][HTML] Redispersible 3D printed nanomedicines: An original application of the semisolid extrusion technique

TV de Oliveira, RS de Oliveira, J Dos Santos… - International Journal of …, 2022 - Elsevier
Semisolid extrusion is a layer-by-layer 3D printing technique that produces objects from gels
or pastes. This process can be carried out at room temperature, without using a light source …

Characterization and Exploration of the Neuroprotective Potential of Oat-Protein-Derived Peptides in PC12 Cells and Scopolamine-Treated Zebrafish

H Rafique, X Hu, T Ren, R Dong, RM Aadil, L Zou… - Nutrients, 2023 - mdpi.com
Neurodegenerative disorders pose a substantial risk to human health, and oxidative stress,
cholinergic dysfunction, and inflammation are the major contributors. The purpose of this …

Differential cytotoxicity of curcumin-loaded micelles on human tumor and stromal cells

XH Do, MHT Hoang, AT Vu, LT Nguyen… - International Journal of …, 2022 - mdpi.com
Although curcumin in the form of nanoparticles has been demonstrated as a potential anti-
tumor compound, the impact of curcumin and nanocurcumin in vitro on normal cells and in …

Nanomedicines Obtained by 3D Printing

NL Funk, J Leão, J dos Santos, JVR de Oliveira… - ADME Processes in …, 2024 - Springer
Nanomedicine encompasses the use of nanotechnology for medical applications. The
development of nano-based drug delivery systems has revealed new possibilities for …

Micronized curcumin causes hyperlocomotion in zebrafish larvae

A Sachett, R Benvenutti, CG Reis… - Neurochemical …, 2022 - Springer
Zebrafish larvae have been widely used in neuroscience and drug research and
development. In the larval stage, zebrafish present a broad behavioral repertoire and …

Curcuma longa: A Natural Ally in Alzheimer's Disease Management

AKS Meneses, GJT Salazar, MM de Freitas… - … : From Traditional to …, 2024 - Springer
The use of plants for the prevention, diagnosis, treatment, and improvement of diseases
dates back to antiquity and has been widely employed in traditional medicine. Among the …

Curcuminoids with Antineurodegenerative Properties: Current Trends and Future Perspectives

LR dos Santos, AA Carvalho, M Rai… - … : From Traditional to …, 2024 - Springer
Curcuminoids are bioactive compounds found in Curcuma longa Linn.(Zingiberaceae), a
species commonly known as turmeric or turmeric root, widely used in traditional medicine for …