Collagen is the major component of the tumor microenvironment and participates in cancer
fibrosis. Collagen biosynthesis can be regulated by cancer cells through mutated genes …

Adipose tissue represents a critical component in healthy energy homeostasis. It fulfills
important roles in whole‐body lipid handling, serves as the body's major energy storage …

Cancer cachexia is a multifactorial condition characterized by body weight loss that
negatively affects quality of life and survival of patients with cancer. Despite the clinical …

Solid tumor growth and metastasis require the interaction of tumor cells with the surrounding
tissue, leading to a view of tumors as tissue-level phenomena rather than exclusively cell …

Cancer cachexia (CC) is a multifactorial syndrome in patients with advanced cancer
characterized by weight loss via skeletal-muscle and adipose-tissue atrophy, catabolic …

Cancer-associated cachexia (CAC) is a hypermetabolic syndrome characterized by
unintended weight loss due to the atrophy of adipose tissue and skeletal muscle. A …

Cachexia is a major cause of morbidity and mortality in individuals with cancer and is
characterized by weight loss due to adipose and muscle tissue wasting. Hallmarks of white …

Lipid droplets are specialized cellular organelles that contain neutral lipid metabolites and
play dynamic roles in energy homeostasis. Perilipin 1 (Plin1), one of the major lipid droplet …

Cachexia is a wasting syndrome characterized by the continuous loss of skeletal muscle
mass due to imbalance between protein synthesis and degradation, which is related with …

Cachexia is a metabolic syndrome consisting of massive loss of muscle mass and function
that has a severe impact on the quality of life and survival of cancer patients. Up to 20% of …