Aggregates of the microtubule-associated protein tau are a defining feature of several
neurodegenerative diseases that are collectively known as tauopathies, and constitute one …

Neurofibrillary tangles and amyloid plaques constitute the hallmark brain lesions of
Alzheimer's disease (AD) patients. Tangles are composed of fibrillar aggregates of the …

Cytoskeletal abnormalities and synaptic loss, typical of both familial and sporadic Alzheimer
disease (AD), are induced by diverse stresses such as neuroinflammation, oxidative stress …

Alzheimer's disease (AD) is an age-related neurodegenerative disorder associated with
progressive memory loss, severe dementia, and hallmark neuropathological markers, such …

Alzheimer's disease (AD) is the most common cause of dementia, affecting more than 36
million people worldwide. AD is characterized by a progressive loss of cognitive functions …

Alzheimer's disease (AD) is the most common origin of dementia in the elderly. Although the
cause of AD remains unknown, several factors have been identified that appear to play a …

Background: Oncology patients experience a large number of symptoms and, those referring
to cognitive performance has an ever-increasing importance in clinical practice, due to the …

Amyloid beta (Aβ) is implicated in Alzheimer's disease (AD) as an integral component of
both neural toxicity and plaque formation. Brains of the longest-lived rodents, naked mole …

The long-lived Chilean rodent (Octodon degus) has been reported to show spontaneous
age-dependent neuropathology and cognitive impairments similar to those observed in …

Alzheimer's disease (AD) is a devastating neurodegenerative disorder in which superior
brain functions, such as memory and cognition, are impaired. Currently, no effective …