Molecular approaches for forensic cell type identification: on mRNA, miRNA, DNA methylation and microbial markers

T Sijen - Forensic Science International: Genetics, 2015 - Elsevier
Human biological traces have the potential to present strong evidence for placing a suspect
at a crime scene. In cases, the activity that led to deposition of an individual's cellular …

[HTML][HTML] DNA modifications: function and applications in normal and disease States

VRB Liyanage, JS Jarmasz, N Murugeshan… - Biology, 2014 - mdpi.com
Epigenetics refers to a variety of processes that have heritable effects on gene expression
programs without changes in DNA sequence. Key players in epigenetic control are chemical …

Landscape of DNA methylation on the X chromosome reflects CpG density, functional chromatin state and X-chromosome inactivation

AM Cotton, EM Price, MJ Jones… - Human molecular …, 2015 - academic.oup.com
X-chromosome inactivation (XCI) achieves dosage compensation between males and
females through the silencing of the majority of genes on one of the female X chromosomes …

Epigenome-associated phenotypic acclimatization to ocean acidification in a reef-building coral

YJ Liew, D Zoccola, Y Li, E Tambutté, AA Venn… - Science …, 2018 - science.org
There are increasing concerns that the current rate of climate change might outpace the
ability of reef-building corals to adapt to future conditions. Work on model systems has …

[HTML][HTML] Ancestral perinatal obesogen exposure results in a transgenerational thrifty phenotype in mice

R Chamorro-Garcia, C Diaz-Castillo… - Nature …, 2017 - nature.com
Ancestral environmental exposures to non-mutagenic agents can exert effects in unexposed
descendants. This transgenerational inheritance has significant implications for …

[HTML][HTML] Phenotypic plasticity: what has DNA methylation got to do with it?

EJ Duncan, CB Cunningham, PK Dearden - Insects, 2022 - mdpi.com
Simple Summary Phenotypic plasticity, the genome producing multiple phenotypes, is
central to an animal's ability to respond to environmental change, expected or otherwise. A …

Causality-enriched epigenetic age uncouples damage and adaptation

K Ying, H Liu, AE Tarkhov, MC Sadler, AT Lu, M Moqri… - Nature aging, 2024 - nature.com
Abstract Machine learning models based on DNA methylation data can predict biological
age but often lack causal insights. By harnessing large-scale genetic data through …

Mammalian epigenetic mechanisms

G Zhang, S Pradhan - IUBMB life, 2014 - Wiley Online Library
The mammalian genome is packaged into chromatin that is further compacted into three‐
dimensional structures consisting of distinct functional domains. The higher order structure …

Signatures of DNA methylation across insects suggest reduced DNA methylation levels in Holometabola

P Provataris, K Meusemann, O Niehuis… - Genome biology and …, 2018 - academic.oup.com
It has been experimentally shown that DNA methylation is involved in the regulation of gene
expression and the silencing of transposable element activity in eukaryotes. The variable …

[HTML][HTML] Parallel Epigenomic and Transcriptomic Responses to Viral Infection in Honey Bees (Apis mellifera)

DA Galbraith, X Yang, EL Nino, S Yi… - PLoS …, 2015 - journals.plos.org
Populations of honey bees are declining throughout the world, with US beekeepers losing
30% of their colonies each winter. Though multiple factors are driving these colony losses, it …