Molecular approaches for forensic cell type identification: on mRNA, miRNA, DNA methylation and microbial markers
T Sijen - Forensic Science International: Genetics, 2015 - Elsevier
Human biological traces have the potential to present strong evidence for placing a suspect
at a crime scene. In cases, the activity that led to deposition of an individual's cellular …
at a crime scene. In cases, the activity that led to deposition of an individual's cellular …
[HTML][HTML] DNA modifications: function and applications in normal and disease States
VRB Liyanage, JS Jarmasz, N Murugeshan… - Biology, 2014 - mdpi.com
Epigenetics refers to a variety of processes that have heritable effects on gene expression
programs without changes in DNA sequence. Key players in epigenetic control are chemical …
programs without changes in DNA sequence. Key players in epigenetic control are chemical …
Landscape of DNA methylation on the X chromosome reflects CpG density, functional chromatin state and X-chromosome inactivation
X-chromosome inactivation (XCI) achieves dosage compensation between males and
females through the silencing of the majority of genes on one of the female X chromosomes …
females through the silencing of the majority of genes on one of the female X chromosomes …
Epigenome-associated phenotypic acclimatization to ocean acidification in a reef-building coral
There are increasing concerns that the current rate of climate change might outpace the
ability of reef-building corals to adapt to future conditions. Work on model systems has …
ability of reef-building corals to adapt to future conditions. Work on model systems has …
[HTML][HTML] Ancestral perinatal obesogen exposure results in a transgenerational thrifty phenotype in mice
R Chamorro-Garcia, C Diaz-Castillo… - Nature …, 2017 - nature.com
Ancestral environmental exposures to non-mutagenic agents can exert effects in unexposed
descendants. This transgenerational inheritance has significant implications for …
descendants. This transgenerational inheritance has significant implications for …
[HTML][HTML] Phenotypic plasticity: what has DNA methylation got to do with it?
Simple Summary Phenotypic plasticity, the genome producing multiple phenotypes, is
central to an animal's ability to respond to environmental change, expected or otherwise. A …
central to an animal's ability to respond to environmental change, expected or otherwise. A …
Causality-enriched epigenetic age uncouples damage and adaptation
Abstract Machine learning models based on DNA methylation data can predict biological
age but often lack causal insights. By harnessing large-scale genetic data through …
age but often lack causal insights. By harnessing large-scale genetic data through …
Mammalian epigenetic mechanisms
G Zhang, S Pradhan - IUBMB life, 2014 - Wiley Online Library
The mammalian genome is packaged into chromatin that is further compacted into three‐
dimensional structures consisting of distinct functional domains. The higher order structure …
dimensional structures consisting of distinct functional domains. The higher order structure …
Signatures of DNA methylation across insects suggest reduced DNA methylation levels in Holometabola
It has been experimentally shown that DNA methylation is involved in the regulation of gene
expression and the silencing of transposable element activity in eukaryotes. The variable …
expression and the silencing of transposable element activity in eukaryotes. The variable …
[HTML][HTML] Parallel Epigenomic and Transcriptomic Responses to Viral Infection in Honey Bees (Apis mellifera)
Populations of honey bees are declining throughout the world, with US beekeepers losing
30% of their colonies each winter. Though multiple factors are driving these colony losses, it …
30% of their colonies each winter. Though multiple factors are driving these colony losses, it …